{"id":"W2160141505","doi":"10.1128/mcb.06726-11","title":"The Role of Ceroid Lipofuscinosis Neuronal Protein 5 (CLN5) in Endosomal Sorting","year":2012,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Hospital for Sick Children; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Retromer; Endosome; Biology; Cell biology; Neuronal ceroid lipofuscinosis; Transport protein; Golgi apparatus; Sorting nexin; Genetics; Gene; Intracellular; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002755732,0.0004317998,0.0001200765,0.0003411402,0.0002881132,0.0004437687,0.0003340486,0.0006939169,0.0002920019],"category_scores_gemma":[0.0002095606,0.0001205915,0.0001802374,0.000119635,0.0004469223,0.0004635201,0.000341256,0.0001713248,0.0001846095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008344683,"about_ca_system_score_gemma":0.0003230685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001213741,"about_ca_topic_score_gemma":0.001242571,"domain_scores_codex":[0.9998562,0.00003151839,0.00002046564,0.00002910099,0.0000334235,0.00002924832],"domain_scores_gemma":[0.9999232,0.00001277307,0.00002472595,0.000007461584,0.000009342069,0.00002250178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003644038,0.00002840656,0.003085786,0.0001369019,0.00001825,0.001205984,0.00004664426,0.0004783846,0.9883033,0.001422081,0.00008347607,0.004826362],"study_design_scores_gemma":[0.0000369553,0.0004094093,0.02329445,0.00004477617,0.00006722417,0.00393617,0.0001618371,0.003728148,0.9616443,0.0007886123,0.005872143,0.00001601594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887182,0.008098545,0.001598059,0.0001922424,0.00002253849,0.00000841192,0.00006538274,0.00002570125,0.001270992],"genre_scores_gemma":[0.9967003,0.001308377,0.0009344648,0.00005488507,0.000005094869,0.000004864248,0.0001072112,0.000003129735,0.0008816029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001213741,"threshold_uncertainty_score":0.006054521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004839581215567429,"score_gpt":0.1987426810473356,"score_spread":0.1939030998317681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}