{"id":"W2160209413","doi":"10.1074/jbc.m405493200","title":"Regulation of Vascular Endothelial Growth Factor Receptor 2-mediated Phosphorylation of Focal Adhesion Kinase by Heat Shock Protein 90 and Src Kinase Activities","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"","keywords":"Proto-oncogene tyrosine-protein kinase Src; Cell biology; Focal adhesion; ASK1; Vascular endothelial growth factor A; Chemistry; Phosphorylation; Heat shock protein; Cancer research; Vascular endothelial growth factor; Mitogen-activated protein kinase kinase; Protein kinase A; Biology; VEGF receptors; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001387028,0.0002963061,0.0001524843,0.0001558319,0.00008743218,0.0002762148,0.0001117817,0.0001762139,0.0008650367],"category_scores_gemma":[0.0001175442,0.0001320648,0.0002685179,0.0001101523,0.0001477383,0.0001485266,0.0001923568,0.0002656066,0.0002589589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002672088,"about_ca_system_score_gemma":0.0001146245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004131447,"about_ca_topic_score_gemma":0.0005536421,"domain_scores_codex":[0.9998086,0.00004541696,0.00001508544,0.00002226555,0.00004037565,0.00006817658],"domain_scores_gemma":[0.9999419,0.000008772436,0.00001839864,0.000005885991,0.000008175663,0.00001679448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001199567,0.00002582381,0.0001117579,0.00002875359,0.000005465762,0.00003363842,0.00001035844,0.00004333559,0.9988193,0.00009556082,0.00003592184,0.000670189],"study_design_scores_gemma":[0.00004136224,0.0003595848,0.01579418,0.000007140661,0.00001620903,0.0002597881,0.00003272083,0.001604288,0.9793606,0.0000694246,0.00244594,0.000008672958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953759,0.002190884,0.0008623254,0.00005513041,0.00002363986,0.00001731917,0.0002129042,0.00002527397,0.001236678],"genre_scores_gemma":[0.9965578,0.001007609,0.0005326464,0.00003741848,0.000009502034,0.00003907644,0.0004312727,0.000004856961,0.001379838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008650367,"threshold_uncertainty_score":0.002893865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01737964295161069,"score_gpt":0.255268746483759,"score_spread":0.2378891035321483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}