{"id":"W2160244237","doi":"10.1128/jb.00400-08","title":"<i>Burkholderia pseudomallei</i>,<i>B. thailandensis</i>, and<i>B. ambifaria</i>Produce 4-Hydroxy-2-Alkylquinoline Analogues with a Methyl Group at the 3 Position That Is Required for Quorum-Sensing Regulation","year":2008,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":144,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Calgary; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Armand-Frappier Foundation","keywords":"Biology; Burkholderia pseudomallei; Microbiology; Burkholderia; Group B; Quorum sensing; Group A; Bacteria; Biofilm; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007295203,0.0002916403,0.0007820707,0.000263394,0.0004847571,0.00003441226,0.00009407568,0.0002360683,0.00004694857],"category_scores_gemma":[0.0001089155,0.000178662,0.0002488294,0.0002452457,0.0003915748,0.0002843201,0.0000596278,0.0003047658,0.000003581027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001347562,"about_ca_system_score_gemma":0.0001113943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007214501,"about_ca_topic_score_gemma":0.00006549107,"domain_scores_codex":[0.9981481,0.0001799679,0.0006822594,0.000362662,0.0002569675,0.0003700867],"domain_scores_gemma":[0.9979346,0.0002223329,0.0008072548,0.0003916223,0.0004817369,0.0001624037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003923035,0.0001553688,0.01124819,0.00007910568,0.0006223377,0.000119962,0.0008713322,0.00001677452,0.972844,0.00006678195,0.007232705,0.00282038],"study_design_scores_gemma":[0.01526584,0.01095173,0.554386,0.0007533976,0.002599936,0.1149865,0.0006157105,0.000668744,0.2502068,0.0005765777,0.04817496,0.0008138287],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832872,0.0009065836,0.003347801,0.01111967,0.0006151461,0.0005655886,0.00001786341,0.00003308751,0.000107082],"genre_scores_gemma":[0.9898739,0.001050996,0.005409166,0.002344289,0.0008785767,0.00001293783,0.00006816815,0.00004637349,0.0003156186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7226373,"threshold_uncertainty_score":0.7285626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0313976676647526,"score_gpt":0.2561547183934026,"score_spread":0.22475705072865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}