{"id":"W2160246564","doi":"10.1095/biolreprod.109.083345","title":"Paternal Exposure to Cyclophosphamide Affects the Progression of Sperm Chromatin Decondensation and Activates a DNA Damage Response in the Prepronuclear Rat Zygote1","year":2010,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"U.S. Public Health Service","keywords":"Biology; Chromatin; Sperm; Protamine; Zygote; Histone; Chromatin remodeling; Cell biology; DNA damage; Andrology; Molecular biology; Genetics; Embryo; DNA; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009696966,0.0003608918,0.0001976726,0.0002964745,0.0001341617,0.000245424,0.0002019611,0.0002001981,0.001442606],"category_scores_gemma":[0.0001238542,0.0001797359,0.0001981748,0.0001200388,0.0001753119,0.0001084533,0.0001430748,0.0003182568,0.000245708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003291678,"about_ca_system_score_gemma":0.0002265439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001606537,"about_ca_topic_score_gemma":0.002225913,"domain_scores_codex":[0.9998896,0.00001441258,0.00001054418,0.00003298562,0.00002367833,0.00002876846],"domain_scores_gemma":[0.9998441,0.0000171484,0.00005442775,0.000017082,0.00001995205,0.00004735299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002238622,0.00001242783,0.0005175196,0.00002740147,0.000004422933,0.00006663369,0.00001249317,0.00001395067,0.99817,0.00003425647,0.00001592779,0.0009010935],"study_design_scores_gemma":[0.00002139006,0.0009177271,0.04995547,0.00001128819,0.00002420012,0.0002450278,0.00005887046,0.0002348216,0.9471787,0.00002361161,0.001321693,0.000007308191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995374,0.002150173,0.001017468,0.00005654382,0.00003054415,0.00001664359,0.0003119359,0.00004854374,0.0009941562],"genre_scores_gemma":[0.9939442,0.00132742,0.0007043214,0.00004648302,0.00001519493,0.0000257684,0.0005012375,0.00001495037,0.003420351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001606537,"threshold_uncertainty_score":0.004826009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01239095188085345,"score_gpt":0.2947670898144674,"score_spread":0.282376137933614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}