{"id":"W2160328993","doi":"10.1073/pnas.1108856108","title":"Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":212,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute","keywords":"Biology; Cell biology; T cell; Nuclear receptor; Cell growth; Receptor; Effector; Immune system; Biochemistry; Transcription factor; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001477567,0.0003692389,0.000281587,0.0002571126,0.0001805757,0.0003479604,0.0001550072,0.0001790438,0.001521876],"category_scores_gemma":[0.0001954953,0.0001739102,0.0002216874,0.0002433644,0.0001621715,0.0001518886,0.0002150347,0.0003333767,0.0007821964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002800369,"about_ca_system_score_gemma":0.0001769785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003680743,"about_ca_topic_score_gemma":0.0004068243,"domain_scores_codex":[0.9998295,0.00003562486,0.00001821912,0.00004663027,0.0000408761,0.00002904775],"domain_scores_gemma":[0.9998844,0.00001445109,0.0000441349,0.00001326557,0.0000246953,0.00001912437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006294815,0.00004954819,0.006178086,0.000411469,0.00006210956,0.0006468521,0.00006518381,0.0003593599,0.9543182,0.0009394801,0.001630684,0.03470961],"study_design_scores_gemma":[0.0001697619,0.001055508,0.09318794,0.000161052,0.000241189,0.006782375,0.0002671571,0.001469133,0.7367815,0.001644991,0.1581947,0.00004475723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7886173,0.1624922,0.02157901,0.001319981,0.0006438888,0.0001440514,0.005276757,0.0009191976,0.01900758],"genre_scores_gemma":[0.950474,0.0324433,0.003544387,0.0002779357,0.0001606398,0.00005095235,0.003073802,0.00005079927,0.009924144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001521876,"threshold_uncertainty_score":0.00509119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02533746873836849,"score_gpt":0.2446946049105815,"score_spread":0.219357136172213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}