{"id":"W2160339712","doi":"10.1902/annals.2001.6.1.113","title":"Receptor for Advanced Glycation End Products, Inflammation, and Accelerated Periodontal Disease in Diabetes: Mechanisms and Insights Into Therapeutic Modalities","year":2001,"lang":"en","type":"review","venue":"Annals of Periodontology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":178,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"","keywords":"Glycation; Rage (emotion); Medicine; Inflammation; Immunoglobulin superfamily; Diabetes mellitus; Receptor; Immunology; Advanced glycation end-product; Disease; Bioinformatics; Internal medicine; Endocrinology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002806144,0.0003655018,0.000863054,0.0002472769,0.0001065373,0.00003257872,0.0002100283,0.0003097211,0.00001286012],"category_scores_gemma":[0.0005945006,0.0003339419,0.00009068353,0.000245798,0.0002924247,0.00003500387,0.0001164975,0.0001503512,0.000001203897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002376969,"about_ca_system_score_gemma":0.0003763608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001855388,"about_ca_topic_score_gemma":0.0001190821,"domain_scores_codex":[0.9978519,0.000279704,0.0006179086,0.0007728136,0.0001297039,0.0003479637],"domain_scores_gemma":[0.9985949,0.00007197424,0.0003407436,0.0004372319,0.0004397717,0.0001154022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003390975,0.00008416244,0.00009179854,0.0110553,0.0001927678,0.00000172608,0.0008454815,0.00001644121,0.0153888,0.002777715,0.0000548703,0.9691519],"study_design_scores_gemma":[0.0005626615,0.0005096536,0.0001383348,0.0006787507,0.00007654831,0.000005479062,0.0001896605,0.00003231067,0.006823036,0.003261509,0.9872325,0.0004895504],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03698287,0.9602186,0.0003829632,0.0006789659,0.0001011094,0.001552561,0.00005590854,0.00001154341,0.00001547955],"genre_scores_gemma":[0.01280691,0.9834376,0.001185545,0.00005985401,0.0001276799,0.0006935977,0.001334874,0.00005239346,0.0003015623],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9871776,"threshold_uncertainty_score":0.9999112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06742903655778042,"score_gpt":0.3694546549184029,"score_spread":0.3020256183606225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}