{"id":"W2160348277","doi":"10.1152/ajpgi.00512.2006","title":"Mice lacking the transcription factor Mist1 exhibit an altered stress response and increased sensitivity to caerulein-induced pancreatitis","year":2006,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Pancreatitis; Acinar cell; Acinus; Unfolded protein response; Transcription factor; Biology; Endocrinology; Internal medicine; Endoplasmic reticulum; Gene expression; Pancreas; Cell biology; Gene; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002234545,0.001485299,0.0006835268,0.001583854,0.0002635517,0.0005815787,0.0003851024,0.001058855,0.002836303],"category_scores_gemma":[0.0003886351,0.0005805976,0.0005226705,0.0005053015,0.0007297071,0.0004765304,0.0004352671,0.00133921,0.0007480925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004391487,"about_ca_system_score_gemma":0.0002016657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004268977,"about_ca_topic_score_gemma":0.0007134958,"domain_scores_codex":[0.9995567,0.00004150352,0.0000721302,0.0001494485,0.00009934573,0.00008089909],"domain_scores_gemma":[0.9987956,0.0001230418,0.000727027,0.00005965593,0.00004166645,0.000252915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004458847,0.0000518994,0.0007828565,0.00005733377,0.0000173436,0.0003700998,0.00003326849,0.00009522666,0.9967001,0.00008257764,0.00007834102,0.001285062],"study_design_scores_gemma":[0.0002591143,0.001930391,0.09115161,0.0000745591,0.0002665744,0.01068248,0.0002488738,0.003221088,0.8846399,0.0004062944,0.00702816,0.00009085474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927855,0.001594867,0.0032015,0.0002175014,0.00006215785,0.00002843116,0.001274781,0.000314079,0.0005212514],"genre_scores_gemma":[0.9864367,0.002066013,0.003940077,0.0001730986,0.00005410507,0.0001002209,0.001867076,0.0002024131,0.005160335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002836303,"threshold_uncertainty_score":0.009488404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007099770918271141,"score_gpt":0.2246023035202916,"score_spread":0.2175025326020205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}