{"id":"W2160350538","doi":"10.1210/en.2008-0481","title":"Temporal Recruitment of Transcription Factors at the 3′,5′-Cyclic Adenosine 5′-Monophosphate-Response Element of the Human GnRH-II Promoter","year":2008,"lang":"en","type":"article","venue":"Endocrinology","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"CREB; Chromatin immunoprecipitation; Biology; CREB1; Response element; CREB-binding protein; Transcription factor; Cyclic AMP Response Element-Binding Protein; Promoter; Internal medicine; Molecular biology; Endocrinology; Phosphorylation; Immunoprecipitation; Cyclic adenosine monophosphate; Endogeny; Cell culture; Cell biology; Gene expression; Gene; Receptor; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323128,0.0001623628,0.0002413615,0.00006125082,0.0004903431,0.000004486266,0.0003989829,0.0000488291,0.0005202138],"category_scores_gemma":[0.00007154643,0.00008791217,0.0001606249,0.0001665068,0.0005015528,0.00005207745,0.0001752643,0.0001750409,0.00001182357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007047375,"about_ca_system_score_gemma":0.00002803077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009960673,"about_ca_topic_score_gemma":0.00001999151,"domain_scores_codex":[0.9982427,0.0004608014,0.0004139062,0.0002850468,0.0002638333,0.0003337398],"domain_scores_gemma":[0.9991919,0.0001184359,0.0002341506,0.0003939842,0.00002529859,0.00003622915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001940838,0.0001568229,0.01074889,0.000008405083,0.000009639542,0.000007447159,0.002062046,0.00001349242,0.9853185,0.0009414125,0.0003254985,0.0002137243],"study_design_scores_gemma":[0.0005280161,0.0004724361,0.02782078,0.00001271228,0.00001437796,0.00003678607,0.00009214535,0.000007881052,0.9492469,0.000142336,0.02154027,0.00008536723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974556,0.0001353832,0.000009368579,0.001033343,0.0003987917,0.000680948,0.00001860612,0.00002620394,0.0002417768],"genre_scores_gemma":[0.997965,0.0000474549,0.00001645832,0.0001442309,0.00002465712,0.00003191866,0.000002455918,0.00001921111,0.001748644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03607164,"threshold_uncertainty_score":0.5695976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1011089744914925,"score_gpt":0.2979576532507412,"score_spread":0.1968486787592487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}