{"id":"W2160350538","doi":"10.1210/en.2008-0481","title":"Temporal Recruitment of Transcription Factors at the 3′,5′-Cyclic Adenosine 5′-Monophosphate-Response Element of the Human GnRH-II Promoter","year":2008,"lang":"en","type":"article","venue":"Endocrinology","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"CREB; Chromatin immunoprecipitation; Biology; CREB1; Response element; CREB-binding protein; Transcription factor; Cyclic AMP Response Element-Binding Protein; Promoter; Internal medicine; Molecular biology; Endocrinology; Phosphorylation; Immunoprecipitation; Cyclic adenosine monophosphate; Endogeny; Cell culture; Cell biology; Gene expression; Gene; Receptor; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001209151,0.0001474637,0.0001687174,0.0001744952,0.0001042608,0.0003037317,0.0001637057,0.0001380251,0.001368171],"category_scores_gemma":[0.0001795047,0.0002235434,0.000217005,0.0001299627,0.0002466381,0.0001570006,0.0001524037,0.0004470471,0.0005054267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003711306,"about_ca_system_score_gemma":0.0002694442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001197905,"about_ca_topic_score_gemma":0.001968367,"domain_scores_codex":[0.9998707,0.0000136209,0.000008454669,0.00004231691,0.00002779902,0.00003712924],"domain_scores_gemma":[0.9999107,0.00002282909,0.00002287743,0.00001076692,0.00001321898,0.00001958095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002260617,0.00001977967,0.0003363647,0.00005000858,0.000002917312,0.00003745059,0.0000292993,0.00002580774,0.9980037,0.000134735,0.00005833084,0.001075571],"study_design_scores_gemma":[0.000047417,0.0002540952,0.02523505,0.00002606328,0.00001868854,0.0003453227,0.0001022083,0.0008771385,0.9670653,0.00009758916,0.005922786,0.000008294817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854556,0.004772542,0.004249618,0.0001908299,0.00007669788,0.00009017615,0.001160198,0.0001183144,0.003885983],"genre_scores_gemma":[0.9906558,0.001435102,0.003322413,0.0001395281,0.00003322727,0.0001086318,0.001158735,0.00002413053,0.003122463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001368171,"threshold_uncertainty_score":0.004576981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1011089744914925,"score_gpt":0.2979576532507412,"score_spread":0.1968486787592487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}