{"id":"W2160401091","doi":"10.1093/hmg/ddl415","title":"Parallel changes in metabolite and expression profiles in crooked-tail mutant and folate-reduced wild-type mice","year":2006,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Metabolite; Biology; Neural tube; Mutant; Homocysteine; Wild type; Internal medicine; Endocrinology; Intracellular; Biochemistry; Genetics; Gene; Embryo; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001790462,0.000542629,0.0004674098,0.002045827,0.0002341874,0.0004393751,0.0003441751,0.0007122087,0.001324766],"category_scores_gemma":[0.0003494083,0.0003649728,0.0005192878,0.000491422,0.0005476531,0.0002414841,0.0003053347,0.0007841412,0.0004355255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004608419,"about_ca_system_score_gemma":0.0001735279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001415229,"about_ca_topic_score_gemma":0.002008002,"domain_scores_codex":[0.9994854,0.00003631465,0.00007170661,0.0002205444,0.0001059134,0.00008012506],"domain_scores_gemma":[0.9992089,0.00008698853,0.0003251955,0.00006760687,0.00007567409,0.0002356954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003798286,0.00002281851,0.001110222,0.00002065,0.00001192675,0.0001199952,0.00003324807,0.00003901726,0.9976587,0.00004419085,0.00002048653,0.0005388194],"study_design_scores_gemma":[0.00007516698,0.0007906536,0.1277237,0.00002168326,0.0001227334,0.002119487,0.0002271878,0.001051032,0.8658668,0.0001784924,0.00177858,0.00004452333],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932882,0.0005285818,0.001994001,0.0000783415,0.00001500181,0.00002327494,0.003424789,0.0001442959,0.0005035182],"genre_scores_gemma":[0.9817559,0.000812486,0.00626306,0.0001688418,0.00001323694,0.0001183022,0.005372026,0.0002167159,0.005279447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002045827,"threshold_uncertainty_score":0.004431784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02064626072650436,"score_gpt":0.2944735713384021,"score_spread":0.2738273106118977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}