{"id":"W2160454557","doi":"10.1128/aac.01159-06","title":"Antiparasitic Drug Nitazoxanide Inhibits the Pyruvate Oxidoreductases of <i>Helicobacter pylori</i> , Selected Anaerobic Bacteria and Parasites, and <i>Campylobacter jejuni</i>","year":2006,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":242,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Health Canada","keywords":"Thiamine pyrophosphate; Anaerobic bacteria; Campylobacter jejuni; Cofactor; Nitazoxanide; Entamoeba histolytica; Biochemistry; Biology; Microbiology; Pyruvate decarboxylation; Chemistry; Pyruvate dehydrogenase complex; Bacteria; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004998502,0.0002682451,0.0001856588,0.00008158691,0.00006984972,0.0001204773,0.0001584846,0.0001623503,0.0006853235],"category_scores_gemma":[0.00006331511,0.00008294766,0.00009753192,0.00008452281,0.0001164345,0.00009914186,0.00008144015,0.0002517406,0.0001918302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002655825,"about_ca_system_score_gemma":0.0000979504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006514833,"about_ca_topic_score_gemma":0.001620314,"domain_scores_codex":[0.9999475,0.000009141492,0.000003689008,0.000009082063,0.00001390576,0.00001655102],"domain_scores_gemma":[0.9999633,0.000005536175,0.00001393108,0.000002003812,0.000005186689,0.000009996593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001898649,0.00001556612,0.0002606759,0.00004010455,0.000006601238,0.00003316301,0.000005725025,0.00002551024,0.9961858,0.00002767722,0.00006281126,0.003146391],"study_design_scores_gemma":[0.00004675614,0.001160354,0.01091174,0.000006371209,0.0000425229,0.0007309543,0.00002445581,0.0007328438,0.9795955,0.00003215964,0.006711694,0.000004679493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848474,0.01024247,0.001769209,0.0001926441,0.00004707689,0.00002084533,0.0002081383,0.0001086364,0.002563599],"genre_scores_gemma":[0.9932341,0.003769461,0.001019457,0.00005923782,0.00001468811,0.000009066714,0.0004157831,0.00001234297,0.00146578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006853235,"threshold_uncertainty_score":0.002292693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007081957431604919,"score_gpt":0.2256319066722463,"score_spread":0.2185499492406414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}