{"id":"W2160473141","doi":"10.1016/j.cardiores.2004.08.004","title":"Critical role of CNS effects of aldosterone in cardiac remodeling post-myocardial infarction in rats","year":2004,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Spironolactone; Internal medicine; Medicine; Aldosterone; Ventricle; Endocrinology; Myocardial infarction; Heart failure; Preload; Fibrosis; Ventricular remodeling; Cardiology; Oral administration; Hemodynamics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001639225,0.0004032085,0.0005720663,0.0003496662,0.0001769283,0.0003072368,0.0001944639,0.000284605,0.001384073],"category_scores_gemma":[0.000172896,0.000174733,0.000253775,0.000125392,0.0004431627,0.0003614067,0.0002009212,0.001060095,0.0002850444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002240371,"about_ca_system_score_gemma":0.0004902637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006743997,"about_ca_topic_score_gemma":0.001233378,"domain_scores_codex":[0.9998302,0.00001931214,0.00001340872,0.00003110394,0.00005216348,0.00005379659],"domain_scores_gemma":[0.999683,0.00001927771,0.00007809587,0.00002977819,0.00003569043,0.0001542057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0058118,0.0004257171,0.002739011,0.0001643671,0.00003028291,0.0003157464,0.0000839433,0.00005837056,0.9785333,0.0001672711,0.0001231265,0.01154697],"study_design_scores_gemma":[0.0006060638,0.01103839,0.1085818,0.00007635466,0.000206067,0.0008760599,0.0005267008,0.0008475183,0.8726367,0.0005202977,0.004040834,0.00004321574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917765,0.004945054,0.001381462,0.0002204157,0.00006374921,0.00003522625,0.0002666608,0.00007885953,0.001232183],"genre_scores_gemma":[0.9932933,0.002655182,0.001519691,0.0001013077,0.00005037741,0.00009971284,0.0002699801,0.00001525759,0.001995285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001384073,"threshold_uncertainty_score":0.004630208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03194326293791352,"score_gpt":0.3353313455450614,"score_spread":0.3033880826071479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}