{"id":"W2160564076","doi":"10.1099/mic.0.051094-0","title":"Enterohaemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha","year":2011,"lang":"en","type":"article","venue":"Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Canada Research Chairs; Ontario Institute for Cancer Research; University of Toronto; University of New Brunswick; Hospital for Sick Children","funders":"Crohn's and Colitis Foundation of Canada; Canadian Institutes of Health Research; Alexander von Humboldt-Stiftung","keywords":"Biology; Flagellin; Secretion; Microbiology; Type three secretion system; Effector; Escherichia coli; Enteropathogenic Escherichia coli; Tumor necrosis factor alpha; Interleukin 8; Virulence; Cytokine; Bacteria; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003003078,0.0003064608,0.0004012002,0.0001220599,0.0001180838,0.00001523712,0.0003406614,0.0002416139,0.00009233705],"category_scores_gemma":[0.0001993297,0.0002843931,0.0002045333,0.0001470704,0.0002231493,0.000007059801,0.000513643,0.0001870224,0.00005750473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005319664,"about_ca_system_score_gemma":0.0001395447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006081562,"about_ca_topic_score_gemma":0.0003017328,"domain_scores_codex":[0.9979758,0.0003703885,0.0004348866,0.0005859993,0.00007746543,0.0005555184],"domain_scores_gemma":[0.9990922,0.00004819779,0.0001768625,0.0003481482,0.0001950389,0.0001395552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001319828,0.0001808224,0.01152313,0.00003822808,0.0001315284,0.000009377631,0.0004506581,0.000004522626,0.9857914,0.000005091973,0.0002417427,0.0003036905],"study_design_scores_gemma":[0.0005151047,0.001310643,0.0245102,0.00001685483,0.00002611722,0.00001629972,0.00003636423,0.000004547406,0.9678379,0.000006244423,0.00546077,0.0002589261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966652,0.0002208697,0.001565992,0.00004606143,0.0004054782,0.0004321974,0.0005128128,0.00002597488,0.0001253722],"genre_scores_gemma":[0.9964628,0.0002484746,0.00188485,0.0003556744,0.0001480152,0.00006584466,0.00005686095,0.00003984519,0.0007376134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01795345,"threshold_uncertainty_score":0.9999608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02778303869339017,"score_gpt":0.2667494811892514,"score_spread":0.2389664424958612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}