{"id":"W2160564076","doi":"10.1099/mic.0.051094-0","title":"Enterohaemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha","year":2011,"lang":"en","type":"article","venue":"Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Canada Research Chairs; Ontario Institute for Cancer Research; University of Toronto; University of New Brunswick; Hospital for Sick Children","funders":"Crohn's and Colitis Foundation of Canada; Canadian Institutes of Health Research; Alexander von Humboldt-Stiftung","keywords":"Biology; Flagellin; Secretion; Microbiology; Type three secretion system; Effector; Escherichia coli; Enteropathogenic Escherichia coli; Tumor necrosis factor alpha; Interleukin 8; Virulence; Cytokine; Bacteria; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001612213,0.0002710882,0.0002925659,0.00008365639,0.00009027239,0.0003130736,0.0001481426,0.0002485342,0.0007738025],"category_scores_gemma":[0.0001341525,0.000116584,0.0002216329,0.0001000831,0.0002162849,0.0001368432,0.0001866736,0.0005220693,0.0002973602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001826417,"about_ca_system_score_gemma":0.000192325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004445359,"about_ca_topic_score_gemma":0.0005638102,"domain_scores_codex":[0.9997346,0.00006410429,0.00003044987,0.00003045037,0.00006127056,0.00007920642],"domain_scores_gemma":[0.9998765,0.00002976703,0.00002830585,0.00002160665,0.0000142041,0.0000296378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001029669,0.00003590012,0.00008067113,0.00001773623,0.000001792319,0.00002396007,0.000009510527,0.00001360361,0.9994681,0.0000176812,0.000007659325,0.0002204567],"study_design_scores_gemma":[0.00001516736,0.0006067636,0.00475254,0.000008074028,0.000007209241,0.0002072655,0.00006364649,0.0003744738,0.9928979,0.00001649947,0.001047381,0.000003092161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978247,0.0004662581,0.0008955721,0.00005312304,0.0000204675,0.00001574376,0.0001334412,0.00001942885,0.0005713066],"genre_scores_gemma":[0.9968919,0.0003992121,0.00103845,0.00004175462,0.000005391238,0.0000233998,0.0003468817,0.000009045481,0.001244031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007738025,"threshold_uncertainty_score":0.002588689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02778303869339017,"score_gpt":0.2667494811892514,"score_spread":0.2389664424958612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}