{"id":"W2160591216","doi":"10.1016/j.jconrel.2013.04.029","title":"Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings","year":2013,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; Associazione Italiana per la Ricerca sul Cancro; Fondazione Umberto Veronesi; Ministero della Salute","keywords":"Nanocarriers; Phage display; Neuroblastoma; In vivo; Ex vivo; Cancer research; Drug delivery; Doxorubicin; Chemistry; Biology; Pharmacology; Peptide; Cell culture; Molecular biology; Medicine; Drug; Chemotherapy; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001402343,0.0002538989,0.001133721,0.0002449772,0.00009248822,0.0000443657,0.0002374936,0.00007220972,0.00006960543],"category_scores_gemma":[0.004304195,0.0001299299,0.0006744229,0.0002311532,0.0001750503,0.0002257253,0.00006456664,0.0008209003,0.00002126821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000558495,"about_ca_system_score_gemma":0.0001765995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005072518,"about_ca_topic_score_gemma":0.000003401971,"domain_scores_codex":[0.9968423,0.000607646,0.001188791,0.00020907,0.0007119234,0.000440334],"domain_scores_gemma":[0.9960169,0.002141376,0.0008910872,0.0002475722,0.0002999015,0.0004031255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.0404598,0.0009736228,0.01911147,0.0003050297,0.001271391,0.001539897,0.000347235,0.0003800739,0.9270308,0.000005863049,0.002467366,0.006107451],"study_design_scores_gemma":[0.4629694,0.02394404,0.188729,0.003115593,0.002849315,0.002429485,0.0007761426,0.02230865,0.2916482,0.0001420639,0.0004147354,0.0006733719],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994887,0.0005777231,0.00005594301,0.002776122,0.0001716722,0.001377598,0.000004705372,0.00001119197,0.0001380207],"genre_scores_gemma":[0.9988988,0.00008444513,0.0002483235,0.0002421679,0.0001406207,0.00003834949,0.000001634079,0.00003366097,0.0003119997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6353826,"threshold_uncertainty_score":0.5298387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007073966046305566,"score_gpt":0.2788146772014513,"score_spread":0.2717407111551458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}