{"id":"W2160635698","doi":"10.1002/pro.157","title":"Fusion order controls expression level and activity of elastin‐like polypeptide fusion proteins","year":2009,"lang":"en","type":"article","venue":"Protein Science","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Elastin; Fusion protein; Fusion; Protein expression; Expression (computer science); Chemistry; Cell biology; Computational biology; Biology; Biochemistry; Genetics; Computer science; Recombinant DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001382229,0.0007196475,0.0007024154,0.0006502786,0.0002988706,0.001385805,0.000530396,0.0007112809,0.001265029],"category_scores_gemma":[0.002435348,0.0005296269,0.0003984724,0.0006881164,0.0006672448,0.0008741961,0.0007764676,0.00177843,0.0009901819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001004071,"about_ca_system_score_gemma":0.0004667553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008690221,"about_ca_topic_score_gemma":0.001316187,"domain_scores_codex":[0.9980859,0.0002524765,0.0002646421,0.0004618558,0.0006333461,0.0003018376],"domain_scores_gemma":[0.997851,0.001003378,0.0003376249,0.000249049,0.0003805084,0.000178468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002473163,0.00002539822,0.0002763488,0.00001890469,0.000002018955,0.00001255066,0.00002441826,0.0000585107,0.9985591,0.00008301967,0.00003818331,0.0008768357],"study_design_scores_gemma":[0.000002904352,0.00004267345,0.001127535,0.000004437004,0.000008435723,0.00005214945,0.00002411135,0.001352662,0.9960652,0.00004813033,0.001265323,0.000006544179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9583911,0.001715439,0.03505918,0.0002728369,0.0001272424,0.0001965517,0.0005717879,0.0007459043,0.002919825],"genre_scores_gemma":[0.967648,0.00121434,0.02418327,0.0002294741,0.00003462219,0.0001626007,0.00169944,0.0006038981,0.004224388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001385805,"threshold_uncertainty_score":0.007310033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02372312404969195,"score_gpt":0.3074668441589983,"score_spread":0.2837437201093063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}