{"id":"W2160655947","doi":"10.1093/hmg/ddi298","title":"Functional promoter SNPs in cell cycle checkpoint genes","year":2005,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Biology; Gene; Genetics; Cell cycle; Promoter; Single-nucleotide polymorphism; Transcription factor; In silico; Gene expression; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002014153,0.0002242449,0.0001475971,0.00009693753,0.0000817981,0.00003946112,0.0001838567,0.0002076806,0.0001045587],"category_scores_gemma":[0.00001312373,0.0002486758,0.0001198389,0.0001037873,0.00006192661,0.000003531084,0.0001317983,0.0001243112,0.00005733824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003098967,"about_ca_system_score_gemma":0.00005560758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009766947,"about_ca_topic_score_gemma":0.0000980185,"domain_scores_codex":[0.9985133,0.00007916895,0.0003621478,0.000475981,0.0002287603,0.0003405805],"domain_scores_gemma":[0.999245,0.000004005008,0.0000913011,0.0004672323,0.00008637498,0.0001061012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001261348,0.0001467265,0.002430706,0.00001210541,0.0000133051,0.00000619947,0.00004144253,0.01020007,0.9827614,0.00006577912,0.0001017295,0.004207946],"study_design_scores_gemma":[0.0007456727,0.0001846847,0.02600748,0.00000657859,0.00001501335,0.000003289247,0.00001414463,0.0005661771,0.9509216,0.0006284354,0.02059426,0.0003126774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821386,0.006923531,0.006653727,0.0001158271,0.00008607451,0.0002437077,0.000006129088,0.00001455984,0.003817795],"genre_scores_gemma":[0.9936811,0.0003325861,0.004456666,0.0002071477,0.0003606136,0.00003189362,0.0001856315,0.00005364225,0.0006907652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03183979,"threshold_uncertainty_score":0.9999965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01339290526830678,"score_gpt":0.2499689339389121,"score_spread":0.2365760286706054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}