{"id":"W2160655947","doi":"10.1093/hmg/ddi298","title":"Functional promoter SNPs in cell cycle checkpoint genes","year":2005,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Biology; Gene; Genetics; Cell cycle; Promoter; Single-nucleotide polymorphism; Transcription factor; In silico; Gene expression; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003852263,0.0003836201,0.0002590036,0.0006245572,0.0001472573,0.0001873496,0.0001546566,0.0003037604,0.001602644],"category_scores_gemma":[0.0008642071,0.000114048,0.0003330104,0.0003693325,0.000229305,0.0000804915,0.0001473029,0.0002973021,0.0002512366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001468403,"about_ca_system_score_gemma":0.0001472219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008058613,"about_ca_topic_score_gemma":0.00140243,"domain_scores_codex":[0.9996835,0.00008789975,0.0000324553,0.00009489648,0.0000668592,0.00003444187],"domain_scores_gemma":[0.999379,0.0003424922,0.0001328743,0.00004414202,0.00004211097,0.00005938224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001501208,0.0001122508,0.1972518,0.0001780504,0.0003520571,0.002048642,0.0003002019,0.001486634,0.7771832,0.0008048567,0.0002729728,0.01850814],"study_design_scores_gemma":[0.0001373781,0.000890527,0.8235108,0.0000868115,0.0006023775,0.01099402,0.0001854692,0.005666665,0.152146,0.001620299,0.004103925,0.00005580719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997084,0.0004198776,0.001649971,0.00004084265,0.00001190992,0.00001259021,0.0003747561,0.00002366064,0.0003825489],"genre_scores_gemma":[0.9987236,0.00008873279,0.0006770947,0.00001846142,0.000007241921,0.000007237288,0.0002970665,0.000007368644,0.0001732482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001602644,"threshold_uncertainty_score":0.005361378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01339290526830678,"score_gpt":0.2499689339389121,"score_spread":0.2365760286706054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}