{"id":"W2160872319","doi":"10.1128/mcb.20.15.5540-5553.2000","title":"Adenovirus E1B 55-Kilodalton Oncoprotein Inhibits p53 Acetylation by PCAF","year":2000,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Université de Sherbrooke","funders":"","keywords":"PCAF; Acetylation; Biology; Transactivation; CREB-binding protein; Molecular biology; Histone; P300-CBP Transcription Factors; DNA; Gene; Biochemistry; Gene expression; Transcription factor; Histone Acetyltransferases; CREB","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003400714,0.000306746,0.0002567416,0.00007612735,0.0001541062,0.00003443979,0.0002664222,0.0004546983,0.0005545416],"category_scores_gemma":[0.00002735575,0.0003006011,0.0001207786,0.000167155,0.0002444996,0.000005893525,0.0001105478,0.0002212768,0.0001630044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000230748,"about_ca_system_score_gemma":0.00007865654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006621415,"about_ca_topic_score_gemma":0.00003243877,"domain_scores_codex":[0.9979166,0.0003368476,0.0002966626,0.0007282167,0.0001674305,0.0005542814],"domain_scores_gemma":[0.999223,0.000009457708,0.00006605304,0.0004447349,0.00006563927,0.0001911424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007275477,0.00007544001,0.0001456801,0.00001175475,0.00006766845,0.00001191868,0.00002356303,0.00002033075,0.9468735,0.00005485113,0.0007407393,0.05124697],"study_design_scores_gemma":[0.001004949,0.001691464,0.0000269752,0.000007089119,0.00001599209,0.00001775151,0.00001156523,0.00004408719,0.9244592,0.0002608232,0.07213121,0.0003289277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840003,0.01163016,0.001479797,0.0003708081,0.00004750717,0.0004142876,0.00004904393,0.00003096272,0.001977162],"genre_scores_gemma":[0.9947363,0.0008278284,0.0001620744,0.0008614746,0.0001430726,0.00005917578,0.0007968277,0.00005603913,0.002357199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07139046,"threshold_uncertainty_score":0.9999446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007380606776330401,"score_gpt":0.2550727036059725,"score_spread":0.2476920968296421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}