{"id":"W2160970655","doi":"10.1085/jgp.201311037","title":"Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy","year":2014,"lang":"en","type":"article","venue":"The Journal of General Physiology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Selectivity; Chemistry; Sodium channel; Sodium; Potassium channel; Potassium; Conductance; Molecular dynamics; Biophysics; Computational chemistry; Biochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005254864,0.0002711864,0.0006196417,0.000182436,0.0004159796,0.001142854,0.0006269051,0.0006104661,0.0006051908],"category_scores_gemma":[0.0008759046,0.0001988567,0.00035015,0.0001960325,0.001018506,0.001099574,0.000808525,0.0006031682,0.0004232157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006492634,"about_ca_system_score_gemma":0.0008037186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001097586,"about_ca_topic_score_gemma":0.001127046,"domain_scores_codex":[0.9997147,0.00005527733,0.00002212267,0.00006209878,0.0001012511,0.00004442222],"domain_scores_gemma":[0.9998541,0.0000396535,0.00002371466,0.00002818916,0.00002855133,0.00002577474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003961276,0.00008750684,0.01111484,0.0007144093,0.0001012624,0.0004771162,0.0005644788,0.03573806,0.8539959,0.06143547,0.0002615039,0.03511334],"study_design_scores_gemma":[0.000338514,0.002058379,0.01862796,0.0001940658,0.0004509171,0.002445943,0.001176202,0.2477123,0.6122751,0.07516998,0.03931283,0.0002377927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9272354,0.002798565,0.0594,0.0008653645,0.00007071283,0.00003964338,0.00009725593,0.0003005941,0.009192429],"genre_scores_gemma":[0.9867525,0.001308502,0.01123569,0.0001316903,0.00001435915,0.00001811957,0.00005291975,0.00002710703,0.0004591611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001142854,"threshold_uncertainty_score":0.004710734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01378666369512697,"score_gpt":0.2357699422655039,"score_spread":0.221983278570377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}