{"id":"W2160971829","doi":"10.1242/dmm.011833","title":"Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening","year":2013,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"RIKEN; Medical Research Council; Genome Canada; University of California, Davis; British Heart Foundation; University of Toronto; European Commission; National Human Genome Research Institute; Wellcome Trust; National Institutes of Health; Cancer Research UK; INFRAFRONTIER; Canadian Institutes of Health Research","keywords":"Context (archaeology); Biology; Gene knockout; Knockout mouse; Embryonic stem cell; Embryo; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002878107,0.000295764,0.0001823123,0.00006326834,0.000359451,0.0001533847,0.0004303336,0.0001537522,0.0003459006],"category_scores_gemma":[0.0002434788,0.0002383791,0.0002270172,0.0001351227,0.00005779074,0.00002030783,0.0003101333,0.0003413873,0.0002287038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003648222,"about_ca_system_score_gemma":0.0001498797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001308987,"about_ca_topic_score_gemma":0.00003499984,"domain_scores_codex":[0.9977621,0.0002018147,0.0002798462,0.0007786657,0.0004578018,0.0005197029],"domain_scores_gemma":[0.9979438,0.0001266773,0.00009048863,0.00129227,0.0001576618,0.0003890692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0016683,0.001404303,0.000118193,0.00005092782,0.0008280261,0.000366396,0.0002842934,0.01340687,0.7724304,0.01233364,0.0430178,0.1540909],"study_design_scores_gemma":[0.006941053,0.001737093,0.003533803,0.0008910821,0.000692021,0.0001193002,0.001870306,0.4061111,0.3927126,0.1510249,0.02948496,0.004881738],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9172447,0.0007086049,0.07529635,0.004158551,0.0002344464,0.001060408,0.0002433697,0.00008123122,0.0009722786],"genre_scores_gemma":[0.9914553,0.0001091654,0.001100676,0.001538339,0.000313556,0.0003425724,0.001132176,0.00008007697,0.003928108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3927042,"threshold_uncertainty_score":0.9720816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03444212962638064,"score_gpt":0.2935376047084371,"score_spread":0.2590954750820564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}