{"id":"W2160991874","doi":"10.1161/atvbaha.115.305438","title":"Deletion of Myeloid GSK3α Attenuates Atherosclerosis and Promotes an M2 Macrophage Phenotype","year":2015,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Macrophage; Phenotype; Myeloid; Immunology; Biology; Inflammation; Cancer research; Medicine; Cell biology; Gene; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002334393,0.00063815,0.0003236947,0.0003629684,0.0001527654,0.0002701436,0.0001965138,0.0002375916,0.001959927],"category_scores_gemma":[0.0001219403,0.0001758993,0.0003526916,0.0001823772,0.0004042292,0.0001760104,0.000209184,0.0006222939,0.000786213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002567818,"about_ca_system_score_gemma":0.0002958192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003226847,"about_ca_topic_score_gemma":0.0006932301,"domain_scores_codex":[0.9998339,0.00003031043,0.00002087153,0.00002789288,0.00003731533,0.00004970055],"domain_scores_gemma":[0.9997578,0.00001570378,0.0001161916,0.00002257784,0.00001475306,0.00007287758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005076631,0.00006220302,0.0003172643,0.00005508817,0.000008030825,0.00005421307,0.00001561752,0.00005642758,0.9977446,0.00007047316,0.0000665298,0.00104195],"study_design_scores_gemma":[0.000197395,0.001148358,0.007821806,0.00003123976,0.00004292437,0.0005203214,0.00006061365,0.0006409441,0.9855941,0.00007425973,0.003860092,0.000007987806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931468,0.002250386,0.001872511,0.0001623679,0.00004718123,0.00004475182,0.0005598418,0.0001778956,0.001738108],"genre_scores_gemma":[0.9930475,0.001257582,0.002094889,0.00007096658,0.00001981938,0.00006716603,0.0004399212,0.00005133578,0.002950911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001959927,"threshold_uncertainty_score":0.006556571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04425752499207188,"score_gpt":0.2823726914551772,"score_spread":0.2381151664631053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}