{"id":"W2161018229","doi":"10.1128/iai.73.10.6372-6382.2005","title":"Live Nonpathogenic Parasitic Vector as a Candidate Vaccine against Visceral Leishmaniasis","year":2005,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":148,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Biology; Leishmania; Immune system; Attenuated vaccine; Immunology; Leishmaniasis; Leishmania donovani; Vaccination; Vector (molecular biology); Virology; Leishmania major; Immunity; Antigen presentation; Antigen; T cell; Visceral leishmaniasis; Microbiology; Parasite hosting; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002966238,0.0002728842,0.0002536369,0.0003347024,0.00008445376,0.0003335029,0.0002745826,0.0004259209,0.001530135],"category_scores_gemma":[0.0001479085,0.00009241003,0.0001384422,0.0001218304,0.0002028964,0.0003753919,0.0001468512,0.0003579243,0.0002860381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001550201,"about_ca_system_score_gemma":0.0002074867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001175745,"about_ca_topic_score_gemma":0.0002001602,"domain_scores_codex":[0.9999081,0.00003528822,0.000005612289,0.00001334418,0.00002034449,0.00001722687],"domain_scores_gemma":[0.9999596,0.000009111686,0.00000804112,0.000005024806,0.00000736669,0.000010926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003518497,0.0002918301,0.0004118169,0.000217556,0.000009500788,0.0001784764,0.00002662868,0.0002124041,0.9825547,0.0008851454,0.0001191299,0.01474105],"study_design_scores_gemma":[0.0005184567,0.01956226,0.005499028,0.0001203132,0.0001728028,0.001939965,0.0001602634,0.002556663,0.9466196,0.001154786,0.02167846,0.00001754999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9739105,0.01430319,0.007935176,0.000599929,0.0001308584,0.0001935389,0.0001395142,0.00009962446,0.002687582],"genre_scores_gemma":[0.9800577,0.008663028,0.00796809,0.00014107,0.00004463641,0.00007085819,0.0003120122,0.00001115173,0.002731417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001530135,"threshold_uncertainty_score":0.005118847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0169673056274331,"score_gpt":0.3060795178097284,"score_spread":0.2891122121822953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}