{"id":"W2161031758","doi":"10.1124/mol.114.093450","title":"Label-Free Monitoring of μ-Opioid Receptor–Mediated Signaling","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Quebec Rehabilitation Research Network; Université de Montréal; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Opioid; Receptor; Cell biology; Pharmacology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004153796,0.0002200042,0.000276602,0.0000841255,0.00007076286,0.00001158552,0.0004545295,0.0002315705,0.0003787851],"category_scores_gemma":[0.0001523587,0.0002319167,0.0001219922,0.0001422421,0.00007822486,0.000004297435,0.0002118362,0.0001611451,0.00002346466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001599646,"about_ca_system_score_gemma":0.00005432285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009635311,"about_ca_topic_score_gemma":4.209033e-7,"domain_scores_codex":[0.9984236,0.0002342681,0.0003512197,0.0004115832,0.0001948918,0.0003843898],"domain_scores_gemma":[0.999145,0.00004112784,0.0001701492,0.000361096,0.0001493634,0.000133254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008180345,0.00007277867,0.0004915742,0.00003324307,0.0001135097,0.000004289988,0.00003624108,0.000283838,0.9960872,0.0001665299,0.001054367,0.001574633],"study_design_scores_gemma":[0.001398777,0.0003981155,0.00002766992,0.00001631506,0.00004157068,0.000004920924,0.00002795258,0.0002465245,0.9771804,0.0002016817,0.02022687,0.0002291556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.975314,0.0009861219,0.02176196,0.0001070708,0.001094609,0.000189792,0.00001404398,0.00003088922,0.0005015553],"genre_scores_gemma":[0.9904085,0.0001424384,0.008258223,0.0003800766,0.0005401435,0.00003627105,0.00007172345,0.00005135993,0.0001112925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01917251,"threshold_uncertainty_score":0.945729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009961288683444971,"score_gpt":0.2641422670028574,"score_spread":0.2541809783194124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}