{"id":"W2161040064","doi":"10.4049/jimmunol.1102797","title":"Plasmacytoid Dendritic Cells and C1q Differentially Regulate Inflammatory Gene Induction by Lupus Immune Complexes","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"CD14; Inflammation; Systemic lupus erythematosus; Immune system; Immunology; CD86; Biology; Microarray analysis techniques; Monocyte; Gene expression; Gene; Cell biology; T cell; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008452363,0.0001722316,0.0005240099,0.0002276353,0.0001285769,0.00001355982,0.0003008073,0.0001555023,0.0002276583],"category_scores_gemma":[0.00008547187,0.0001087618,0.00009348166,0.0001051082,0.0004872119,0.0001132783,0.0001406391,0.0005365849,0.00002317894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001010052,"about_ca_system_score_gemma":0.0001122472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005732754,"about_ca_topic_score_gemma":0.000007254416,"domain_scores_codex":[0.998095,0.0004259851,0.0007311542,0.0001159657,0.0003026439,0.0003292137],"domain_scores_gemma":[0.9986379,0.0001751493,0.0004617922,0.000367043,0.0002657986,0.0000923913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001402642,0.00009248435,0.00519093,0.00008639856,0.0004856453,0.00006665778,0.002638969,5.291063e-7,0.988395,0.00005065254,0.0008601293,0.0007299251],"study_design_scores_gemma":[0.004620775,0.001250625,0.02216264,0.0003894513,0.0002895539,0.157759,0.002321395,0.00002521433,0.80971,0.0004714009,0.000832782,0.000167145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887632,0.00937591,0.0001303087,0.0002856273,0.001011433,0.000244864,0.000003195853,0.0000168779,0.0001686224],"genre_scores_gemma":[0.9955628,0.002923436,0.0002217372,0.00003026146,0.0001283704,0.000003084675,0.000002471902,0.00003109334,0.001096772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.178685,"threshold_uncertainty_score":0.4435176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02301992947241688,"score_gpt":0.2482685477067143,"score_spread":0.2252486182342974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}