{"id":"W2161043620","doi":"10.1128/jvi.80.3.1140-1151.2006","title":"Myxoma Virus M11L Blocks Apoptosis through Inhibition of Conformational Activation of Bax at the Mitochondria","year":2006,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Apoptosis; Biology; Cytoplasm; Transfection; Mitochondrion; Virus; Molecular biology; Myxoma virus; Cell biology; Virology; Cell culture; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002898355,0.00009445478,0.0001922663,0.00007455957,0.00005878372,0.000004847622,0.0001539754,0.0001597709,0.0001526112],"category_scores_gemma":[0.00005351875,0.00006918459,0.0001304377,0.0000999146,0.000213037,0.00001375485,0.00005854416,0.0001376701,0.000002736622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002807752,"about_ca_system_score_gemma":0.00009879363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003292134,"about_ca_topic_score_gemma":0.0000615122,"domain_scores_codex":[0.9988441,0.0001202807,0.0005315111,0.00009253137,0.0002652638,0.0001463322],"domain_scores_gemma":[0.9987875,0.00005428158,0.000627576,0.000180067,0.000326737,0.00002379324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003290349,0.0001031099,0.0002646252,0.00000997502,0.00008182368,5.566465e-7,0.0000560377,0.001798117,0.9880562,0.00008087845,0.005954904,0.0003033631],"study_design_scores_gemma":[0.001043738,0.002267488,0.001168535,0.00001052246,0.00002042135,0.0000359655,0.00003308251,0.00005303873,0.9896666,0.000701535,0.004941754,0.00005734952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971642,0.000282087,0.0009092573,0.0007738571,0.00009908071,0.0001078012,0.00002650556,0.000001279548,0.0006358997],"genre_scores_gemma":[0.9988856,0.000147614,0.0002362275,0.0002536829,0.0002727689,0.000004254074,0.0000507485,0.000009647177,0.0001394833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00224661,"threshold_uncertainty_score":0.2821266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0119810979421911,"score_gpt":0.2767368063725321,"score_spread":0.264755708430341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}