{"id":"W2161070527","doi":"10.7150/thno.9265","title":"Hair Metabolomics: Identification of Fetal Compromise Provides Proof of Concept for Biomarker Discovery","year":2014,"lang":"en","type":"article","venue":"Theranostics","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Medical Research Council; National Medical Research Council; Worldwide Universities Network; Science Foundation Ireland; University of Auckland; Singapore Institute for Clinical Sciences","keywords":"Metabolome; Metabolomics; Metabolite; Biomarker discovery; Biomarker; Metabolite profiling; Biology; Computational biology; Bioinformatics; Physiology; Proteomics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003016972,0.0001299856,0.0002982946,0.00004317723,0.00002883944,0.00001170589,0.0001647129,0.00007733246,0.000001389622],"category_scores_gemma":[0.0003779164,0.0001098963,0.0001287818,0.00006382742,0.0001994844,0.000005873459,0.00005864279,0.0000289341,1.479627e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000437145,"about_ca_system_score_gemma":0.00003075121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006678741,"about_ca_topic_score_gemma":0.000004563325,"domain_scores_codex":[0.999096,0.00005068375,0.0003948956,0.0002194224,0.00009500088,0.0001440331],"domain_scores_gemma":[0.9991193,0.00006657463,0.0003099805,0.0003102322,0.0001691951,0.00002468837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002186162,0.0001093856,0.0003372612,0.00008709288,0.0001956624,3.061728e-8,0.00005880258,0.00008412637,0.9918212,0.003411457,0.0002133558,0.003462992],"study_design_scores_gemma":[0.0008692548,0.0003020066,0.001761277,0.00000949025,0.0001016338,7.164003e-7,0.00005458109,0.001300661,0.9870657,0.001218749,0.007188656,0.000127235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.771268,0.002102516,0.2254896,0.00008185567,0.0002276081,0.0005541404,0.0001817585,0.00001309869,0.00008148405],"genre_scores_gemma":[0.9961606,0.0001211597,0.003174923,0.00003220207,0.00009402719,0.00003176968,0.00009279922,0.00003610227,0.0002563877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2248927,"threshold_uncertainty_score":0.4481441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0141323678989565,"score_gpt":0.2561186668373656,"score_spread":0.2419862989384091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}