{"id":"W2161095279","doi":"10.1001/jama.294.17.2203","title":"Randomized trials stopped early for benefit: a systematic review.","year":2005,"lang":"en","type":"review","venue":"PubMed","topic":"Meta-analysis and systematic reviews","field":"Decision Sciences","cited_by":696,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Randomized controlled trial; Interim; Interim analysis; Sample size determination; Psychological intervention; Clinical trial; MEDLINE; Intervention (counseling); Family medicine; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","metaepi_broad","scholarly_communication","open_science","insufficient_payload"],"consensus_categories":["metaresearch","metaepi_narrow","metaepi_broad","insufficient_payload"],"category_scores_codex":[0.7783436,0.001620924,0.165354,0.001324951,0.0001917453,0.002243855,0.006183225,0.0005511381,0.00228732],"category_scores_gemma":[0.7392275,0.0005960234,0.06628966,0.002635925,0.00009789076,0.0002949581,0.0002323,0.0003979599,0.004564583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001861065,"about_ca_system_score_gemma":0.0001892538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003117265,"about_ca_topic_score_gemma":0.0000047039,"domain_scores_codex":[0.6184522,0.2163151,0.1445476,0.004332097,0.01467797,0.001674993],"domain_scores_gemma":[0.6283139,0.2409239,0.1113279,0.01524735,0.00332543,0.0008614913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009053953,0.00001925113,3.828997e-8,0.4671119,0.002327916,8.851559e-7,0.00001171995,1.130948e-7,2.144149e-10,0.0006357884,0.02012034,0.5096815],"study_design_scores_gemma":[0.009258688,0.000005391911,3.22037e-7,0.1604901,0.07408299,0.00001993233,0.000005087879,0.00001753007,5.731524e-9,0.000938974,0.7547153,0.0004656595],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[9.656085e-8,0.8707352,0.002686388,0.0002703193,0.0007982467,0.1231024,0.0002455825,0.00002037586,0.002141407],"genre_scores_gemma":[7.0088e-7,0.7717561,0.000736593,0.0003653865,0.0005290894,0.1735622,0.00006392438,0.00007517985,0.0529109],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.734595,"threshold_uncertainty_score":0.9996538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8865896086510653,"score_gpt":0.5833323863289361,"score_spread":0.3032572223221291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}