{"id":"W2161129289","doi":"10.1074/jbc.m708887200","title":"A Role for the Cleaved Cytoplasmic Domain of E-cadherin in the Nucleus","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Cadherin; Nuclear localization sequence; Cell biology; Nucleus; Cytosol; Cytoplasm; Intracellular; Cell nucleus; Nuclear transport; Cleavage (geology); Biology; Mediator; Catenin; Nuclear protein; Cell; Signal transduction; Transcription factor; Biochemistry; Wnt signaling pathway; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001345275,0.0002553916,0.0001540161,0.0001203783,0.0002406046,0.0005665424,0.000254735,0.0004999295,0.001136828],"category_scores_gemma":[0.0001502466,0.0001084924,0.0001662238,0.00007959297,0.0005058668,0.0005829789,0.0002496197,0.0004530846,0.0004102204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004142904,"about_ca_system_score_gemma":0.0003026535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002762827,"about_ca_topic_score_gemma":0.0004976162,"domain_scores_codex":[0.9999087,0.00001444103,0.000004970395,0.00002907195,0.00002614728,0.00001669068],"domain_scores_gemma":[0.9998721,0.0000203634,0.00002200671,0.00001970363,0.00003281048,0.00003302433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006807702,0.00001485723,0.0002979046,0.00005454947,0.000003271851,0.0003675102,0.00002336604,0.00003702968,0.9955333,0.001704841,0.00007034594,0.00182472],"study_design_scores_gemma":[0.0000739295,0.0003876408,0.0101691,0.00002929639,0.00002241896,0.00346176,0.0001485189,0.00149435,0.9724379,0.001292783,0.01046811,0.00001422886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9507713,0.02210844,0.0184304,0.001166573,0.0001736587,0.0000328953,0.0001912265,0.0001400729,0.00698538],"genre_scores_gemma":[0.9909731,0.002557294,0.00339491,0.0001051132,0.00001710161,0.0000127606,0.0001851964,0.000008700802,0.002745742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001136828,"threshold_uncertainty_score":0.003803134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02333345001397895,"score_gpt":0.2452927705500869,"score_spread":0.2219593205361079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}