{"id":"W2161156606","doi":"10.1016/s1053-2498(00)00166-2","title":"Transplant immunosuppression increases and prolongs transgene expression following adenoviral-mediated transfection of rat lungs","year":2000,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Transgene; Immunosuppression; Transfection; Genetic enhancement; Immune system; Transplantation; Immunology; Medicine; Inflammation; In vivo; Biology; Cancer research; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004463283,0.0004194877,0.0005863215,0.0006130242,0.0002647298,0.0007301325,0.0003774903,0.0004534984,0.001651536],"category_scores_gemma":[0.0003977072,0.0002816616,0.0006722468,0.0003522853,0.0005327107,0.0007011821,0.0002690802,0.001380075,0.0004665646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005078086,"about_ca_system_score_gemma":0.0004590731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000874039,"about_ca_topic_score_gemma":0.001590042,"domain_scores_codex":[0.9996401,0.0000406836,0.00004060739,0.00006649671,0.00006705475,0.000144957],"domain_scores_gemma":[0.9990808,0.0003487717,0.0001955838,0.000113545,0.00005829587,0.0002030912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000480245,0.00006387704,0.0001656787,0.00002607371,0.000005330409,0.00006109489,0.00003172449,0.00004165507,0.9981419,0.0001741049,0.00002627964,0.0007819716],"study_design_scores_gemma":[0.00001336201,0.0003398474,0.002125649,0.000005587341,0.00001836728,0.0001064767,0.00002314635,0.0003055701,0.9964796,0.00003145445,0.0005470845,0.000003836602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939586,0.002383501,0.001887608,0.0001244232,0.00007310533,0.00002086854,0.0002675577,0.0001056897,0.001178615],"genre_scores_gemma":[0.9932452,0.001263932,0.001109639,0.00005929127,0.00004717371,0.00003061533,0.0005726814,0.00006422934,0.003607241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001651536,"threshold_uncertainty_score":0.005524874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006307432597526565,"score_gpt":0.2596503095307114,"score_spread":0.2533428769331849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}