{"id":"W2161287236","doi":"10.1006/jmbi.2000.3842","title":"Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein","year":2000,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":163,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Medical Research Council","keywords":"Dihedral angle; Chemistry; Crystallography; Hydrogen bond; Residual dipolar coupling; Side chain; Protonation; Peptide bond; Dipole; Protein structure; Nuclear magnetic resonance spectroscopy; Stereochemistry; Peptide; Molecule","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003582636,0.0001810374,0.000325069,0.00007056817,0.00006364654,0.00001105773,0.0003655672,0.0002095437,0.000005994733],"category_scores_gemma":[0.00006604606,0.0001216782,0.0001188205,0.0001988091,0.0001859255,0.000006543616,0.00007591425,0.0001242198,6.230089e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003174221,"about_ca_system_score_gemma":0.0002233414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000962549,"about_ca_topic_score_gemma":0.00008401731,"domain_scores_codex":[0.9987335,0.0001163084,0.0005032477,0.0002138366,0.0001991563,0.000233995],"domain_scores_gemma":[0.998772,0.000009615605,0.0005020939,0.0003385799,0.0003080438,0.00006966777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007103475,0.00003990744,0.001616169,0.00003934553,0.0001531238,0.000009487554,0.00003409883,0.004757795,0.9896559,0.0004030895,0.000009989807,0.002570735],"study_design_scores_gemma":[0.0005943097,0.001468437,0.0006518827,0.0001173267,0.00007613635,0.0002416813,0.00006664241,0.0001610933,0.9954575,0.0005156526,0.000483306,0.0001660138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9114369,0.0008609116,0.08690812,0.000165622,0.0000274202,0.0005075285,0.00004595225,0.000002764722,0.00004482362],"genre_scores_gemma":[0.982112,0.0000371847,0.01755286,0.0000917514,0.0001340765,0.00001262292,0.00001651597,0.00001747808,0.00002551127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07067513,"threshold_uncertainty_score":0.4961894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003799448795946484,"score_gpt":0.2471398812820952,"score_spread":0.2433404324861488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}