{"id":"W2161308975","doi":"10.4049/jimmunol.169.8.4467","title":"Synergistic Engagement of an Ineffective Endogenous Anti-Tumor Immune Response and Induction of IFN-γ and Fas-Ligand-Dependent Tumor Eradication by Combined Administration of IL-18 and IL-2","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"National Cancer Institute; National Institutes of Health","keywords":"Endogeny; Immune system; Fas ligand; Cytokine; In vivo; Immunology; Cancer research; CD8; Biology; Ex vivo; Apoptosis; Endocrinology; Programmed cell death; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008663475,0.0001135309,0.0002752986,0.00009436513,0.00007254451,0.000005562041,0.0001122913,0.00007196274,0.000006432949],"category_scores_gemma":[0.0002198987,0.0000897899,0.00003452974,0.00005966572,0.0003348101,0.00001792075,0.00005595788,0.0001429756,1.280484e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001000566,"about_ca_system_score_gemma":0.00004079391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002916806,"about_ca_topic_score_gemma":0.00000262333,"domain_scores_codex":[0.998684,0.0005197332,0.000493872,0.0001026122,0.00009340936,0.0001063795],"domain_scores_gemma":[0.9988266,0.00008483045,0.0007138251,0.0001838203,0.0001689538,0.00002192042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0033412,0.0001957948,0.0001744067,0.00003190526,0.0002067805,0.00000327577,0.0006814646,0.000009490315,0.9931559,0.00001935576,0.00001237922,0.002168032],"study_design_scores_gemma":[0.001870854,0.006379443,0.03025968,0.00003003774,0.0001068836,0.0003935333,0.001193883,0.00003223264,0.9595394,0.00005092805,0.00006511047,0.00007805388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929128,0.006595936,0.00009661693,0.0001004698,0.00006826055,0.0001815763,0.00001919154,0.00000143413,0.00002368767],"genre_scores_gemma":[0.997427,0.002462792,0.00004329435,0.00001375859,0.00001341532,0.000003113817,0.00001186788,0.00000924251,0.00001544279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03361656,"threshold_uncertainty_score":0.3661526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01298228498379285,"score_gpt":0.2299495960520918,"score_spread":0.216967311068299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}