{"id":"W2161309706","doi":"10.1152/ajpendo.00006.2010","title":"Cultured hypothalamic neurons are resistant to inflammation and insulin resistance induced by saturated fatty acids","year":2010,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Insulin resistance; Inflammation; Internal medicine; Endocrinology; Chemistry; Insulin; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001352044,0.0002126371,0.0005348996,0.0001560256,0.0002407825,0.00003263754,0.0002479591,0.00008751376,0.00001193686],"category_scores_gemma":[0.0005980943,0.0001695216,0.00006070203,0.0003438148,0.0006653522,0.0002554186,0.00008764366,0.0006955085,0.000005688177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000882109,"about_ca_system_score_gemma":0.00004216169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001164839,"about_ca_topic_score_gemma":0.00002835607,"domain_scores_codex":[0.9983307,0.000364539,0.0004328043,0.0003761911,0.0001521605,0.0003436115],"domain_scores_gemma":[0.9985695,0.0001967448,0.00066825,0.0002264737,0.0001478924,0.0001911411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004471722,0.00003177113,0.0002312986,0.000005669595,0.00001585078,0.0000103044,0.0002294352,0.000002447145,0.9907424,0.001635636,0.0001702632,0.006477769],"study_design_scores_gemma":[0.0005806605,0.000152015,0.4972906,0.000009936777,0.00002561843,0.00008286573,0.000131876,0.000002989495,0.486318,0.0008887172,0.01438268,0.0001340222],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954168,0.0002978917,0.00001631924,0.003607927,0.0003944297,0.0001335652,0.00002055799,0.00002695871,0.00008550815],"genre_scores_gemma":[0.9974273,0.0006643062,0.0007823948,0.0008423074,0.0001942453,0.00000505066,0.000001879608,0.00001343886,0.00006911135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5044244,"threshold_uncertainty_score":0.6912891,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01106256630387972,"score_gpt":0.2444550604700758,"score_spread":0.233392494166196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}