{"id":"W2161323699","doi":"10.1128/iai.00485-09","title":"Antiapoptotic Proteins Bcl-2 and Bcl-X <sub>L</sub> Inhibit <i>Clostridium difficile</i> Toxin A-Induced Cell Death in Human Epithelial Cells","year":2009,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Clostridium difficile toxin A; Apoptosis; Programmed cell death; Biology; Caspase 8; Cell; Cell culture; Cell biology; Caspase; Cancer research; Molecular biology; Microbiology; Clostridium difficile; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001941719,0.0004178275,0.0003818973,0.000294141,0.0001999553,0.0002996769,0.0002437931,0.0002560208,0.00152947],"category_scores_gemma":[0.0001463986,0.0001350553,0.0003269537,0.0002896097,0.0001516096,0.0001700962,0.0002299358,0.0006284958,0.0006403396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000287143,"about_ca_system_score_gemma":0.0003271477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006637077,"about_ca_topic_score_gemma":0.0009877622,"domain_scores_codex":[0.9997476,0.00005025272,0.00002895314,0.00003251979,0.00007378118,0.0000669502],"domain_scores_gemma":[0.999895,0.00002508288,0.00002345888,0.00001713794,0.00002056533,0.00001871347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002638372,0.0001600438,0.0002231172,0.0001001615,0.00001255084,0.00007544464,0.0000344892,0.00007239529,0.9945996,0.0001138553,0.0002161122,0.004128518],"study_design_scores_gemma":[0.00008164864,0.0007748613,0.002469589,0.00000863637,0.00002363142,0.0003826685,0.00002409865,0.0006120862,0.9896395,0.00002362585,0.00595592,0.000003876746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9690962,0.01523279,0.008748956,0.0003528603,0.0001559741,0.0001712169,0.0006930079,0.0003165001,0.00523253],"genre_scores_gemma":[0.9828702,0.00603854,0.00569463,0.0002096975,0.00004238121,0.0001919613,0.001386595,0.00002945855,0.003536524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00152947,"threshold_uncertainty_score":0.005116642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02167541369548508,"score_gpt":0.2750950385410061,"score_spread":0.253419624845521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}