{"id":"W2161340954","doi":"10.1128/jvi.01445-10","title":"Nuclear Export of Human Papillomavirus Type 31 E1 Is Regulated by Cdk2 Phosphorylation and Required for Viral Genome Maintenance","year":2010,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Helicase; Nuclear export signal; Nuclear transport; Origin recognition complex; DNA replication; Control of chromosome duplication; Cell biology; Pre-replication complex; Viral replication; Minichromosome maintenance; S phase; Eukaryotic DNA replication; Viral life cycle; Replication factor C; Cell nucleus; DNA; Genetics; Gene; Virus; Nucleus; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009003459,0.0002470703,0.0001669072,0.0001262435,0.0002464771,0.0003812191,0.0001362956,0.0001155729,0.0009790849],"category_scores_gemma":[0.0001566843,0.0001259114,0.0001480611,0.00007973807,0.0002172279,0.0002508826,0.0002384428,0.0002059974,0.0005001465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000457025,"about_ca_system_score_gemma":0.0002597718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001005305,"about_ca_topic_score_gemma":0.001350447,"domain_scores_codex":[0.9999158,0.00001015413,0.0000094885,0.00002411236,0.0000179167,0.00002249895],"domain_scores_gemma":[0.9998916,0.00001367742,0.00003076977,0.00001296057,0.00001476005,0.00003618888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000196159,0.00003350266,0.000852685,0.00002497096,0.000002477008,0.00008760775,0.00001495215,0.00008252724,0.9975556,0.0001754472,0.00003806619,0.0009359163],"study_design_scores_gemma":[0.00003697096,0.0001630406,0.03373266,0.000009031793,0.000008792013,0.0005500407,0.00007005611,0.002102536,0.9594808,0.0001989934,0.003639939,0.000007198438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956892,0.0016311,0.00113599,0.00006631352,0.00001943814,0.000009896902,0.0001535658,0.00006583708,0.001228668],"genre_scores_gemma":[0.9970055,0.0005672988,0.0004848622,0.00001407403,0.000003928088,0.0000096124,0.0002475768,0.00001518584,0.001651911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001005305,"threshold_uncertainty_score":0.003315926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006086366509380948,"score_gpt":0.2349378088453658,"score_spread":0.2288514423359849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}