{"id":"W2161340954","doi":"10.1128/jvi.01445-10","title":"Nuclear Export of Human Papillomavirus Type 31 E1 Is Regulated by Cdk2 Phosphorylation and Required for Viral Genome Maintenance","year":2010,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Helicase; Nuclear export signal; Nuclear transport; Origin recognition complex; DNA replication; Control of chromosome duplication; Cell biology; Pre-replication complex; Viral replication; Minichromosome maintenance; S phase; Eukaryotic DNA replication; Viral life cycle; Replication factor C; Cell nucleus; DNA; Genetics; Gene; Virus; Nucleus; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001592102,0.00008268325,0.000174224,0.00003538177,0.00005086028,0.000006109073,0.00008513081,0.0002191291,0.00004533859],"category_scores_gemma":[0.00003760084,0.00007129766,0.00006524463,0.0000291668,0.0001064779,0.000007840967,0.00002597208,0.0001226619,9.708687e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005624059,"about_ca_system_score_gemma":0.0000205904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003942933,"about_ca_topic_score_gemma":0.000002812153,"domain_scores_codex":[0.9994023,0.00001588368,0.0002794644,0.0001258703,0.00005819562,0.0001182715],"domain_scores_gemma":[0.9993363,0.000005063408,0.0003303155,0.0001323829,0.0001499857,0.00004592354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007163059,0.00002061694,0.0004628897,0.000006707101,0.00005239882,0.000001565843,0.00004981375,0.000001083846,0.9902787,0.0001401045,0.007340512,0.0009293603],"study_design_scores_gemma":[0.002906664,0.007051851,0.04725365,0.0000102139,0.0001222345,0.0003197156,0.00006584347,0.00007017155,0.6537386,0.002334195,0.2858709,0.0002560551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989109,0.0002879488,0.00009760683,0.0001818938,0.0003011867,0.00007225073,0.0000100766,0.000002367865,0.0001357798],"genre_scores_gemma":[0.9982797,0.0001203271,0.0006993423,0.0003377554,0.0002074475,5.481812e-7,0.00002050897,0.00001681304,0.0003175461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3365401,"threshold_uncertainty_score":0.2907434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006086366509380948,"score_gpt":0.2349378088453658,"score_spread":0.2288514423359849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}