{"id":"W2161352421","doi":"10.1002/acn3.187","title":"Predictors of disability worsening in clinically isolated syndrome","year":2015,"lang":"en","type":"article","venue":"Annals of Clinical and Translational Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Centre intégré de santé et de services sociaux de Chaudière-Appalaches; Hôpital Notre-Dame; Hôpital Charles-Le Moyne","funders":"National Health and Medical Research Council; Teva Pharmaceutical Industries; Univerzita Karlova v Praze; Biogen; Sanofi","keywords":"Medicine; Internal medicine; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002038868,0.00009043713,0.0007204658,0.00006080145,0.0000124419,0.000001395489,0.00006833252,0.0001712884,0.00002473603],"category_scores_gemma":[0.002814758,0.00007181163,0.0001542172,0.0001667413,0.001248927,0.00005257476,0.00003965342,0.0003939039,0.000001610983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":2.881104e-7,"about_ca_system_score_gemma":0.00009803198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000418187,"about_ca_topic_score_gemma":0.00003646213,"domain_scores_codex":[0.997436,0.0003620252,0.001442231,0.0002726837,0.0003066517,0.0001804129],"domain_scores_gemma":[0.9966573,0.002569435,0.0001636025,0.0001510113,0.0002502202,0.000208465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006205669,0.0006105448,0.9882508,0.0000515729,0.00009207267,0.00001612946,0.00008774611,0.00004749262,0.00001307857,0.0001190842,0.00004938443,0.004456423],"study_design_scores_gemma":[0.002631956,0.003012757,0.9909471,0.00003106361,0.00001743989,0.00001244322,0.000007299458,0.001451442,0.00000781623,0.001538701,0.0002982817,0.00004373884],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838254,0.0001718667,0.000027522,0.01527839,0.00009499241,0.0002196873,0.00002245984,0.000009880314,0.0003498451],"genre_scores_gemma":[0.9988316,0.0004108628,0.0001901217,0.000481201,0.0000557015,0.000004981072,0.00001078694,0.000006327169,0.000008379273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01500628,"threshold_uncertainty_score":0.4601725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2861374047466109,"score_gpt":0.4702445684595193,"score_spread":0.1841071637129084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}