{"id":"W2161359562","doi":"10.1128/ec.00236-12","title":"Normal Adaptation of Candida albicans to the Murine Gastrointestinal Tract Requires Efg1p-Dependent Regulation of Metabolic and Host Defense Genes","year":2012,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Biology; Candida albicans; Microbiology; Cecum; Mutant; Corpus albicans; Gene expression; Gastrointestinal tract; Gene; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008050263,0.0004257579,0.0001926036,0.0003124377,0.0001559969,0.0002344325,0.0001985184,0.0002971443,0.0007248734],"category_scores_gemma":[0.0001049808,0.0001405195,0.0002208387,0.0001717627,0.0002514659,0.0001255521,0.0002632915,0.0006232808,0.0003300017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003652665,"about_ca_system_score_gemma":0.000194381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007218798,"about_ca_topic_score_gemma":0.001008118,"domain_scores_codex":[0.999824,0.00001681231,0.00001286662,0.00005015481,0.00003680764,0.0000593529],"domain_scores_gemma":[0.9998544,0.00001336531,0.00004092139,0.00002507455,0.00001750962,0.00004869472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008897794,0.00001683323,0.0002229313,0.000009259114,0.000001042132,0.00003136574,0.000007360982,0.00002923422,0.9989379,0.00003318413,0.00001995231,0.0006020073],"study_design_scores_gemma":[0.00001304473,0.0002003001,0.02679577,0.00001097357,0.00000696456,0.0002329079,0.00004677093,0.0009086289,0.9702401,0.0000586125,0.001478522,0.000007543819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955565,0.0009043674,0.00161462,0.00007416643,0.00001308255,0.00001963736,0.0008951283,0.00009964416,0.0008229739],"genre_scores_gemma":[0.9934377,0.0003464202,0.00200951,0.00005507645,0.000004381776,0.00007586292,0.001255132,0.00004154737,0.002774293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007248734,"threshold_uncertainty_score":0.002650261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01966054700669537,"score_gpt":0.250923265812894,"score_spread":0.2312627188061986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}