{"id":"W2161359562","doi":"10.1128/ec.00236-12","title":"Normal Adaptation of Candida albicans to the Murine Gastrointestinal Tract Requires Efg1p-Dependent Regulation of Metabolic and Host Defense Genes","year":2012,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Biology; Candida albicans; Microbiology; Cecum; Mutant; Corpus albicans; Gene expression; Gastrointestinal tract; Gene; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004285921,0.0001079327,0.0002445018,0.00005822963,0.00004568171,0.000004522914,0.00005336685,0.00002653013,0.0002100998],"category_scores_gemma":[0.0001295673,0.00007552436,0.00006209215,0.000123409,0.0000870185,0.0000929782,0.00002879449,0.00008105845,0.00001022126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001770708,"about_ca_system_score_gemma":0.0000664403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007246305,"about_ca_topic_score_gemma":0.0004557727,"domain_scores_codex":[0.9990009,0.00004769696,0.0003186665,0.0001418371,0.0002856638,0.0002052395],"domain_scores_gemma":[0.9992498,0.0001113634,0.0001383045,0.0002532872,0.0001185441,0.0001287684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003782932,0.0002308954,0.9617156,0.0001395992,0.00001090526,0.000002888343,0.0009722576,0.0001210892,0.03437051,0.0001513239,0.00006410246,0.001842528],"study_design_scores_gemma":[0.0004790589,0.0002664135,0.9765207,0.00006659443,0.000139683,0.00005293706,0.0008401887,0.0003614632,0.02109732,0.00000594519,0.0001081786,0.00006151725],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946848,0.001835776,0.001784041,0.0001951181,0.00005724614,0.000307584,0.00001551443,0.000008467675,0.001111439],"genre_scores_gemma":[0.9967955,0.00005236772,0.001896534,0.00004351763,0.0001198504,0.000004518895,0.00001134603,0.00001001589,0.001066401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01480509,"threshold_uncertainty_score":0.3079794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01966054700669537,"score_gpt":0.250923265812894,"score_spread":0.2312627188061986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}