{"id":"W2161472051","doi":"10.1002/prot.24777","title":"Unprecedented access of phenolic substrates to the heme active site of a catalase: Substrate binding and peroxidase-like reactivity of<i>Bacillus pumilus</i>catalase monitored by X-ray crystallography and EPR spectroscopy","year":2015,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Enzyme-mediated dye degradation","field":"Agricultural and Biological Sciences","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Research Council Canada; Western Economic Diversification Canada; Canadian Institutes of Health Research; University of Saskatchewan","keywords":"Peroxidase; Bacillus pumilus; Catalase; Reactivity (psychology); Electron paramagnetic resonance; Substrate (aquarium); Heme; Chemistry; Photochemistry; Enzyme; Biochemistry; Nuclear magnetic resonance; Bacteria; Biology; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006975733,0.0002152049,0.0001313209,0.0000777128,0.0001044695,0.0002669771,0.0003311858,0.0002850439,0.000425873],"category_scores_gemma":[0.0001497381,0.0001247249,0.00009713579,0.0001018504,0.0001590929,0.0001439147,0.0001837798,0.0004108963,0.0001460461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001693846,"about_ca_system_score_gemma":0.00007339125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002588323,"about_ca_topic_score_gemma":0.0001195018,"domain_scores_codex":[0.9999416,0.00000974613,0.000001899201,0.00001640221,0.00001766092,0.00001275862],"domain_scores_gemma":[0.9999392,0.00001013639,0.00001751783,0.000003865997,0.0000100288,0.00001920784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006374669,0.00002146161,0.0009144936,0.00004575316,0.000007035712,0.0001321788,0.00003594962,0.0001469166,0.9968682,0.0001146076,0.00008291736,0.001566826],"study_design_scores_gemma":[0.00001837341,0.0002607827,0.01289907,0.000007823165,0.0000157192,0.001223608,0.0000878054,0.004265072,0.9785523,0.0001824226,0.002473005,0.00001395503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974394,0.0005879714,0.001386675,0.00006104624,0.000004480352,0.000002571385,0.00003742545,0.00005192913,0.0004283927],"genre_scores_gemma":[0.9985966,0.0002135424,0.0008007054,0.00001912376,0.00000277616,0.000003129935,0.0001056744,0.000007919307,0.0002505489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000425873,"threshold_uncertainty_score":0.00142467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0143176148703616,"score_gpt":0.2178996328382635,"score_spread":0.2035820179679019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}