{"id":"W2161472051","doi":"10.1002/prot.24777","title":"Unprecedented access of phenolic substrates to the heme active site of a catalase: Substrate binding and peroxidase-like reactivity of<i>Bacillus pumilus</i>catalase monitored by X-ray crystallography and EPR spectroscopy","year":2015,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Enzyme-mediated dye degradation","field":"Agricultural and Biological Sciences","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Research Council Canada; Western Economic Diversification Canada; Canadian Institutes of Health Research; University of Saskatchewan","keywords":"Peroxidase; Bacillus pumilus; Catalase; Reactivity (psychology); Electron paramagnetic resonance; Substrate (aquarium); Heme; Chemistry; Photochemistry; Enzyme; Biochemistry; Nuclear magnetic resonance; Bacteria; Biology; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002004139,0.0001990426,0.0002658657,0.00006595747,0.0001201828,0.00008069666,0.0001207574,0.0001473122,0.000007751137],"category_scores_gemma":[0.0000711545,0.00008488227,0.00003755296,0.0005861332,0.0002041652,0.0005582408,0.00008641019,0.0001756715,3.686695e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001715294,"about_ca_system_score_gemma":0.00001807983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004239339,"about_ca_topic_score_gemma":0.0004175277,"domain_scores_codex":[0.9989129,0.00005415448,0.0003820114,0.000182431,0.0002837274,0.0001847487],"domain_scores_gemma":[0.9990586,0.00008167779,0.0004381124,0.0000935264,0.0001809127,0.0001471816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003302604,0.00004507661,0.01831216,0.0001158374,0.00004738479,2.019732e-7,0.001258037,0.00001073748,0.9739763,0.00001307905,0.00009845159,0.005792452],"study_design_scores_gemma":[0.0008395446,0.001027407,0.1894369,0.00008393438,0.00009121612,0.00001130997,0.004410765,0.0005577187,0.8026196,0.00019712,0.0004433284,0.0002811397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977018,0.0001604145,0.0001143193,0.000195237,0.00007241063,0.000716437,0.000992627,0.00002299629,0.0000237484],"genre_scores_gemma":[0.9988297,0.00008468689,0.0005311192,0.00003356258,0.00003109455,0.00001427649,0.0004669185,0.000002012685,0.000006618613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1713568,"threshold_uncertainty_score":0.3461398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0143176148703616,"score_gpt":0.2178996328382635,"score_spread":0.2035820179679019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}