{"id":"W2161518213","doi":"10.1128/mcb.00024-15","title":"Fission Yeast Cdk7 Controls Gene Expression through both Its CAK and C-Terminal Domain Kinase Activities","year":2015,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Cyclin-dependent kinase 7; Biology; Cyclin-dependent kinase 1; Cyclin-dependent kinase 9; Cyclin-dependent kinase; RNA polymerase II; Schizosaccharomyces pombe; Cell biology; Cyclin-dependent kinase 2; Mitogen-activated protein kinase kinase; Cyclin-dependent kinase 4; Biochemistry; Kinase; Protein kinase A; Molecular biology; Promoter; Gene expression; Gene; Saccharomyces cerevisiae; Cell cycle","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003721452,0.0003057413,0.0001521699,0.0001812041,0.0001384632,0.0002538675,0.0001678154,0.0001083421,0.0007482201],"category_scores_gemma":[0.00008115076,0.00008627048,0.0001546306,0.0001425873,0.0001920589,0.0001345816,0.0001659323,0.0002056595,0.0004447162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004219615,"about_ca_system_score_gemma":0.0002222699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001339282,"about_ca_topic_score_gemma":0.001955821,"domain_scores_codex":[0.9999372,0.000004951782,0.000003948116,0.00002164958,0.00001784107,0.00001441744],"domain_scores_gemma":[0.9999567,0.000005633939,0.00001163018,0.000006337997,0.000008436824,0.00001120686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001300755,0.000009272483,0.000678198,0.00003012145,0.000003308256,0.0000458055,0.00000861302,0.000139841,0.9966599,0.0002324151,0.00005286893,0.002009505],"study_design_scores_gemma":[0.0000128328,0.00004976829,0.009681192,0.000005208661,0.0000109982,0.0001746662,0.00003419184,0.001900057,0.9829149,0.0001766894,0.00503242,0.000006894665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916857,0.001537187,0.002967485,0.00006899418,0.00002057064,0.00001038017,0.001312941,0.0001122078,0.002284406],"genre_scores_gemma":[0.9955115,0.0006184531,0.001352202,0.00001439102,0.000004234465,0.000009556074,0.001125626,0.00003177661,0.001332184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001339282,"threshold_uncertainty_score":0.003061533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01642892115387698,"score_gpt":0.2700863033410617,"score_spread":0.2536573821871847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}