{"id":"W2161642637","doi":"10.1093/molehr/gan030","title":"Reduced meiotic recombination on the XY bivalent is correlated with an increased incidence of sex chromosome aneuploidy in men with non-obstructive azoospermia","year":2008,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary General Hospital; University of Calgary","funders":"University of California, San Francisco; University of California, San Diego","keywords":"Aneuploidy; Biology; Azoospermia; Andrology; Meiosis; Sperm; Male infertility; Bivalent (engine); Obstructive azoospermia; Infertility; Gynecology; Genetics; Chromosome; Medicine; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000281143,0.0002611365,0.0002900671,0.001044393,0.000286704,0.0003248175,0.0001925439,0.0002722631,0.001556466],"category_scores_gemma":[0.001256892,0.000287446,0.0001535533,0.0003790834,0.0003888091,0.0001500015,0.0002561126,0.0002803488,0.0001289969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007803696,"about_ca_system_score_gemma":0.00006553122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005715918,"about_ca_topic_score_gemma":0.0007211888,"domain_scores_codex":[0.9997453,0.00005977841,0.00002919875,0.00006247302,0.00006818034,0.00003506512],"domain_scores_gemma":[0.9991181,0.0001755454,0.0004543629,0.00005412217,0.00004930113,0.0001484899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004844115,0.00002946055,0.9771448,0.00003234627,0.00006705519,0.0007327627,0.0002022408,0.00005919338,0.0175935,0.00004058819,0.00004748798,0.003566194],"study_design_scores_gemma":[0.000005711559,0.0002449813,0.9953461,0.000002825405,0.00002544628,0.003275558,0.00006875191,0.0000669021,0.0008447742,0.000019358,0.00009673747,0.00000290839],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994761,0.0003133959,0.00007625514,0.000007581473,0.000001856211,0.000001204372,0.000016141,0.000003196652,0.0001042319],"genre_scores_gemma":[0.9997266,0.00007856939,0.0000497495,0.000006236027,0.000005789061,8.958917e-7,0.00003337563,8.975276e-7,0.00009780245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001556466,"threshold_uncertainty_score":0.005206883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01422483650312285,"score_gpt":0.246488432132477,"score_spread":0.2322635956293542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}