{"id":"W2161692381","doi":"10.1093/annonc/mdr021","title":"Southwest Oncology Group study S0413: a phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer","year":2011,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Gastric Cancer Management and Outcomes","field":"Medicine","cited_by":160,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency; Response Biomedical (Canada)","funders":"National Cancer Institute; U.S. Department of Health and Human Services","keywords":"Medicine; Lapatinib; Internal medicine; Cancer; Metastatic breast cancer; Oncology; Crizotinib; Angiogenesis; Phases of clinical research; Epidermal growth factor receptor; Gastroenterology; Breast cancer; Chemotherapy; Trastuzumab; Lung cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002410386,0.001878589,0.00314899,0.0006301783,0.0004755552,0.001121101,0.001064726,0.001368643,0.006771531],"category_scores_gemma":[0.001227317,0.0007423331,0.002587759,0.0009179434,0.001503268,0.001020902,0.0006643666,0.003627516,0.001309442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00145251,"about_ca_system_score_gemma":0.003354352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00215935,"about_ca_topic_score_gemma":0.008199438,"domain_scores_codex":[0.9993192,0.0004167508,0.00003209551,0.00008189227,0.00003975661,0.0001103779],"domain_scores_gemma":[0.9991087,0.0001258828,0.0001763463,0.00008198355,0.00003818087,0.0004687359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9164011,0.01929972,0.009979422,0.0005710545,0.001998219,0.0001401261,0.0001243464,0.001846874,0.007022418,0.000230853,0.007651061,0.03473485],"study_design_scores_gemma":[0.8997447,0.08473084,0.01083608,0.00002761556,0.0008468398,0.0001494236,0.00005284712,0.0008025327,0.000715672,0.0001812386,0.001886868,0.00002540035],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990393,0.001539024,0.0002779573,0.001101755,0.000228927,0.001542125,0.003009752,0.0001129053,0.001794601],"genre_scores_gemma":[0.9759477,0.002713688,0.00209809,0.002111997,0.0004019755,0.0029163,0.009924782,0.00007671127,0.003808812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006771531,"threshold_uncertainty_score":0.02265304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1451100644784034,"score_gpt":0.4255288335353503,"score_spread":0.2804187690569468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}