{"id":"W2161706773","doi":"10.1128/aac.01688-10","title":"AmpG Inactivation Restores Susceptibility of Pan-β-Lactam-Resistant Pseudomonas aeruginosa Clinical Strains","year":2011,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Microbiology; Efflux; Imipenem; Aztreonam; Pseudomonas aeruginosa; Ceftazidime; Piperacillin; Population; Biology; Mutant; Meropenem; Cefepime; Cefpirome; Cephalosporin; Antibiotics; Bacteria; Antibiotic resistance; Biochemistry; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007862158,0.0004832181,0.000376709,0.0002601574,0.00007942927,0.0002967746,0.0002383153,0.0002469963,0.0009342373],"category_scores_gemma":[0.0002413747,0.0001354133,0.0002162267,0.0001664644,0.0001846711,0.0001237962,0.0003229577,0.0004838304,0.0003038383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001563657,"about_ca_system_score_gemma":0.0001862704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006673081,"about_ca_topic_score_gemma":0.0004971083,"domain_scores_codex":[0.9998074,0.00002366679,0.00002294883,0.00003581521,0.00007414717,0.00003595974],"domain_scores_gemma":[0.9998618,0.0000200701,0.00004343903,0.00002450776,0.00001634469,0.00003382687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000643587,0.00004115725,0.0002120673,0.00001689704,0.000003712651,0.000054914,0.000008996899,0.00003030335,0.9985095,0.00001349175,0.00001574363,0.001028953],"study_design_scores_gemma":[0.0000208467,0.0007175311,0.01182559,0.000007780414,0.00002239728,0.0006023037,0.00004635809,0.0009252217,0.9842466,0.00003549757,0.001541991,0.000007883719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979846,0.0003867872,0.0007618271,0.00005442708,0.00001273375,0.0000280762,0.0002382845,0.0001022488,0.0004309735],"genre_scores_gemma":[0.9972643,0.0002961296,0.0008822746,0.00004251468,0.000007488495,0.00002410371,0.0004480009,0.00003304239,0.001002228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009342373,"threshold_uncertainty_score":0.00312537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03445425071594441,"score_gpt":0.2946817556330023,"score_spread":0.2602275049170578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}