{"id":"W2161751938","doi":"10.1158/0008-5472.can-05-0436","title":"Targeted Elimination of Prostate Cancer by Genetically Directed Human T Lymphocytes","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Antigen; Chimeric antigen receptor; Cancer research; In vivo; Prostate cancer; Cancer; Glutamate carboxypeptidase II; Adoptive cell transfer; Immunology; T cell; Prostate; Biology; Medicine; Immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001456258,0.0003886186,0.0002546121,0.0001756956,0.00008066223,0.0003077786,0.0001896114,0.0002858366,0.0008435979],"category_scores_gemma":[0.0001328221,0.00009010597,0.0002626717,0.0001025106,0.0001491347,0.000107411,0.0001311312,0.0006502654,0.0004173647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001711898,"about_ca_system_score_gemma":0.0003070576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004142851,"about_ca_topic_score_gemma":0.0004758457,"domain_scores_codex":[0.9998533,0.00003043586,0.000006075133,0.00003074727,0.00003607,0.00004339501],"domain_scores_gemma":[0.9999561,0.00001192471,0.00001048295,0.000009080019,0.000004148997,0.000008243022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002978805,0.0002121762,0.0003172031,0.0001057064,0.00001744554,0.0001149793,0.00003672775,0.0003980465,0.9801002,0.0004791509,0.0003791814,0.01754123],"study_design_scores_gemma":[0.0002352096,0.003629613,0.002038917,0.00002576502,0.00007469732,0.0009671872,0.00002231417,0.002437515,0.9756967,0.0001819826,0.01468033,0.00000980397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9600658,0.008856467,0.02413823,0.0003608718,0.0001314022,0.0002937635,0.0003109097,0.0007483587,0.005094195],"genre_scores_gemma":[0.9884171,0.002787063,0.005246643,0.0002119263,0.0000564761,0.0001464152,0.0003345691,0.00003728843,0.002762618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008435979,"threshold_uncertainty_score":0.002822101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05288526224692186,"score_gpt":0.4252216114787874,"score_spread":0.3723363492318655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}