{"id":"W2161779103","doi":"10.1007/s10571-014-0054-9","title":"Ciliary Neurotrophic Factor Reverses Aberrant Mitochondrial Bioenergetics Through the JAK/STAT Pathway in Cultured Sensory Neurons Derived from Streptozotocin-Induced Diabetic Rodents","year":2014,"lang":"en","type":"article","venue":"Cellular and Molecular Neurobiology","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Ciliary neurotrophic factor; Internal medicine; Biology; Endocrinology; Axon; Neurite; Neurotrophic factors; Mitochondrial biogenesis; Mitochondrion; Cell biology; Neuroscience; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002002575,0.0003630214,0.000363962,0.0004235654,0.0002476226,0.0004407445,0.0002940634,0.000286166,0.0007989217],"category_scores_gemma":[0.0001524973,0.0001530133,0.0003595657,0.0002559537,0.0003516895,0.0003004066,0.0001603563,0.001281652,0.0001944081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003990396,"about_ca_system_score_gemma":0.0006241695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003346122,"about_ca_topic_score_gemma":0.007769777,"domain_scores_codex":[0.9998395,0.00001287951,0.00002612549,0.00002717103,0.00003873374,0.00005549521],"domain_scores_gemma":[0.9998575,0.00001521281,0.00003282721,0.00001642433,0.00002027946,0.00005777218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006186895,0.00006998936,0.0003366303,0.000057334,0.00001432825,0.0001363938,0.00002503507,0.00004592422,0.9971222,0.00009816575,0.00005513872,0.001420108],"study_design_scores_gemma":[0.000143525,0.000681844,0.008242153,0.00001880763,0.00009592492,0.0002610259,0.0001389416,0.0008555682,0.9878774,0.0001159398,0.00155906,0.000009782176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996696,0.001118296,0.0006915033,0.0001121137,0.0000754137,0.00001594275,0.0003001502,0.00003408868,0.0009564119],"genre_scores_gemma":[0.996695,0.0008617264,0.0005580306,0.00004138652,0.00001213026,0.00001828641,0.0003652548,0.000013117,0.001435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003346122,"threshold_uncertainty_score":0.006653249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02488175240194022,"score_gpt":0.2377321606199067,"score_spread":0.2128504082179665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}