{"id":"W2161779103","doi":"10.1007/s10571-014-0054-9","title":"Ciliary Neurotrophic Factor Reverses Aberrant Mitochondrial Bioenergetics Through the JAK/STAT Pathway in Cultured Sensory Neurons Derived from Streptozotocin-Induced Diabetic Rodents","year":2014,"lang":"en","type":"article","venue":"Cellular and Molecular Neurobiology","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Ciliary neurotrophic factor; Internal medicine; Biology; Endocrinology; Axon; Neurite; Neurotrophic factors; Mitochondrial biogenesis; Mitochondrion; Cell biology; Neuroscience; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006770618,0.0004067318,0.0003966687,0.00007759014,0.0002816684,0.00007715595,0.0004011812,0.0002525524,0.00002447966],"category_scores_gemma":[0.0004321189,0.0002969133,0.0001588467,0.0002093775,0.0003443428,0.0001129673,0.0001952752,0.0005147771,0.00002208322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001753634,"about_ca_system_score_gemma":0.00004112022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008205487,"about_ca_topic_score_gemma":0.00003560195,"domain_scores_codex":[0.9958419,0.001942014,0.0004544276,0.001033505,0.000196616,0.0005314925],"domain_scores_gemma":[0.9987358,0.0002878133,0.000180568,0.0006422506,0.00003815204,0.0001154073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006703832,0.00008377827,0.00008239921,0.00001022225,0.000009305415,0.0001544682,0.0002642494,0.0002772236,0.9983767,0.000329598,0.00004440844,0.0003006012],"study_design_scores_gemma":[0.0009825657,0.0003125481,0.000476945,0.00001447647,0.00002687951,0.00002257902,0.00002507569,0.0007214082,0.9945514,0.0005173712,0.002034935,0.0003138704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947675,0.0001521292,0.001285311,0.0008819273,0.001987636,0.0006964225,0.00008499461,0.00006627618,0.00007780944],"genre_scores_gemma":[0.9963126,0.0001212476,0.0001248175,0.002978216,0.0002039459,0.0000454303,0.00005860536,0.00004964085,0.0001055361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003825362,"threshold_uncertainty_score":0.9999483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02488175240194022,"score_gpt":0.2377321606199067,"score_spread":0.2128504082179665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}