{"id":"W2161820875","doi":"10.1016/j.yexcr.2004.05.009","title":"Expression profiles of p53 and p66shc during oxidative stress-induced senescence in fetal bovine fibroblasts","year":2004,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research; National Science Council; University of Guelph","keywords":"Senescence; Biology; Oxidative stress; Fetal bovine serum; Cell biology; Somatic cell; Population; Cell culture; Cell; Cell cycle; Molecular biology; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001690109,0.0001426526,0.0001677362,0.0004816649,0.0003077619,0.0003663558,0.0001021555,0.0001947041,0.001123095],"category_scores_gemma":[0.0001889995,0.0001201908,0.0002130486,0.0003721339,0.0002434925,0.0002229478,0.0001194763,0.0003089834,0.0003347535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003420573,"about_ca_system_score_gemma":0.0002366675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004116967,"about_ca_topic_score_gemma":0.002535345,"domain_scores_codex":[0.999854,0.00001779715,0.00001715551,0.00003139328,0.00002770611,0.00005204094],"domain_scores_gemma":[0.9998296,0.00004842117,0.00002765807,0.00001625131,0.00003936767,0.00003861787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004590433,0.00001504979,0.0009427378,0.00002289559,0.000004538282,0.00009958952,0.0001224463,0.00003269589,0.9971519,0.000125951,0.00003187775,0.0009913252],"study_design_scores_gemma":[0.00002579878,0.0005277575,0.07905184,0.00001245255,0.00004356836,0.0006658379,0.0006531081,0.000902943,0.9141546,0.0001394504,0.003804675,0.00001793045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945422,0.002021982,0.001072022,0.00005468445,0.00002633681,0.000009837574,0.0007965905,0.00002010187,0.001456359],"genre_scores_gemma":[0.9927953,0.00112231,0.0007793559,0.00004427863,0.00001304832,0.00002757355,0.00105909,0.000008634767,0.004150481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004116967,"threshold_uncertainty_score":0.008185983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03730252143261283,"score_gpt":0.3519498959847964,"score_spread":0.3146473745521836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}