{"id":"W2161858472","doi":"10.1186/ar4237","title":"Treatment of Muckle-Wells syndrome: analysis of two IL-1-blocking regimens","year":2013,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Canakinumab; Anakinra; Medicine; Internal medicine; Rheumatology; Gastroenterology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007685646,0.0004000249,0.000878486,0.0003546001,0.0001552385,0.0003999267,0.0004037713,0.0004423846,0.001210339],"category_scores_gemma":[0.0008616808,0.000114842,0.000695891,0.0002635663,0.0002394329,0.0003800434,0.0001708384,0.0006999102,0.0001525789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004439707,"about_ca_system_score_gemma":0.0003468508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002488863,"about_ca_topic_score_gemma":0.0004989906,"domain_scores_codex":[0.9995901,0.0001755702,0.00004834913,0.00006279031,0.00006396131,0.0000592212],"domain_scores_gemma":[0.9995446,0.0001718078,0.0001054406,0.00004407696,0.00002603042,0.0001081228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.2547667,0.02236831,0.03080452,0.001520225,0.00254716,0.0005071467,0.0003558985,0.002537122,0.07169127,0.0008205328,0.0009106737,0.6111705],"study_design_scores_gemma":[0.1740692,0.6194324,0.1493968,0.0004843131,0.003603145,0.00293871,0.0002505263,0.004297532,0.02756506,0.0006240147,0.01724321,0.00009507572],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793684,0.01822096,0.0004736681,0.0001738154,0.0000728711,0.0002267069,0.0001225997,0.00002229238,0.001318636],"genre_scores_gemma":[0.9924898,0.00542172,0.0008342728,0.0002268928,0.0001069533,0.0002668969,0.0002313817,0.000005501715,0.0004165697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001210339,"threshold_uncertainty_score":0.00406456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02627454293596605,"score_gpt":0.3260115038001148,"score_spread":0.2997369608641488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}