{"id":"W2161868337","doi":"10.4049/jimmunol.1300726","title":"Optimized Tetramer Analysis Reveals Ly49 Promiscuity for MHC Ligands","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre; McGill University; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Tetramer; Promiscuity; Major histocompatibility complex; Biology; Chemistry; Genetics; Biochemistry; Immune system; Ecology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001657591,0.0002792013,0.0002343196,0.0003018467,0.0001299021,0.0003530078,0.0003314796,0.0002828001,0.001981913],"category_scores_gemma":[0.0002332937,0.0001324372,0.0001949497,0.000274046,0.000126159,0.0001395469,0.0001286397,0.0004735301,0.0009190181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003027242,"about_ca_system_score_gemma":0.0001140256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005798573,"about_ca_topic_score_gemma":0.0007827478,"domain_scores_codex":[0.9997792,0.00004193878,0.00001696027,0.00005447941,0.00005327666,0.00005424642],"domain_scores_gemma":[0.9998544,0.00003696266,0.00002439406,0.00002340194,0.00003193946,0.00002882207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005570447,0.000006891738,0.0001090637,0.000005336479,0.000001818768,0.0000130645,0.000006594606,0.00006536486,0.999246,0.00004187934,0.00001778268,0.0004305945],"study_design_scores_gemma":[0.000009415987,0.00007277287,0.001909347,0.000002020179,0.000006928838,0.0001143669,0.00001485764,0.003617429,0.993437,0.0000332766,0.0007784267,0.000004087921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806361,0.0003533329,0.0164894,0.00006957251,0.00001052536,0.00003970934,0.0006644946,0.0001511301,0.001585763],"genre_scores_gemma":[0.9837275,0.0002878467,0.01172738,0.00006923075,0.00000462298,0.00005472354,0.001821646,0.00009160029,0.002215513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001981913,"threshold_uncertainty_score":0.006630182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01233664263411706,"score_gpt":0.2461656336750816,"score_spread":0.2338289910409645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}