{"id":"W2161873485","doi":"10.1210/en.2006-1674","title":"Compartmentalization of Signaling-Competent Epidermal Growth Factor Receptors in Endosomes","year":2007,"lang":"en","type":"article","venue":"Endocrinology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Endosome; Endocytic cycle; Cell biology; Epidermal growth factor; Phosphorylation; Biology; Tyrosine phosphorylation; Compartmentalization (fire protection); Endocytosis; Intracellular; Tyrosine; Epidermal growth factor receptor; Tyrosine kinase; Signal transduction; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001556162,0.0002475657,0.0002555031,0.0001862369,0.0001271792,0.0002633111,0.0001561102,0.0002016545,0.0004225507],"category_scores_gemma":[0.0001442432,0.0001211831,0.0002610375,0.00009634566,0.0001374724,0.0003618521,0.0002110566,0.0003797411,0.0002604721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002693895,"about_ca_system_score_gemma":0.0001770342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003012208,"about_ca_topic_score_gemma":0.0004262099,"domain_scores_codex":[0.9998866,0.00002029077,0.000008894322,0.00002933597,0.000027704,0.00002716254],"domain_scores_gemma":[0.9999266,0.0000182794,0.00001542525,0.00001438991,0.00001317995,0.00001215494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003815021,0.000002896084,0.00007224133,0.00002089052,0.000003386517,0.00002258235,0.000006794543,0.00001588729,0.9993045,0.00004959206,0.000003751323,0.0004593671],"study_design_scores_gemma":[0.000006015221,0.00005307592,0.002283374,0.000003582568,0.00001139799,0.0002323646,0.00002107561,0.000292285,0.9961697,0.00005408802,0.0008702698,0.000002707789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990496,0.00202118,0.006548289,0.0000726654,0.00001573374,0.00002659804,0.0002129202,0.00003683135,0.0005698412],"genre_scores_gemma":[0.9908345,0.001729871,0.005440061,0.0000495431,0.0000101343,0.00003544554,0.0004760052,0.00002716924,0.001397225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004225507,"threshold_uncertainty_score":0.001954496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392686577599222,"score_gpt":0.2475063152542118,"score_spread":0.2335794494782195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}