{"id":"W2161899881","doi":"10.1186/1476-4598-13-101","title":"Lactate Dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma","year":2014,"lang":"en","type":"article","venue":"Molecular Cancer","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":197,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Sunnybrook Health Science Centre; St. Michael's Hospital; Western University; London Health Sciences Centre; University Health Network; University of Toronto; York University","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada; Prostate Cancer Canada","keywords":"Lactate dehydrogenase A; Renal cell carcinoma; Lactate dehydrogenase; Immunohistochemistry; Biology; Clear cell renal cell carcinoma; Oncology; Cancer; Pathology; Clear cell; Proportional hazards model; Clinical significance; Internal medicine; Metastasis; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001772731,0.000282516,0.0002510855,0.00008690586,0.00005801924,0.00003793489,0.000242387,0.0002002703,0.0001513427],"category_scores_gemma":[0.00002405007,0.0002931039,0.0002049124,0.0001642417,0.00007052882,0.000006444957,0.0001306751,0.0001792737,0.00003235823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000371971,"about_ca_system_score_gemma":0.0002100947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003556117,"about_ca_topic_score_gemma":0.00016742,"domain_scores_codex":[0.9981782,0.000135224,0.0002729056,0.0006375381,0.0002373475,0.0005387118],"domain_scores_gemma":[0.99915,0.000005351805,0.0001044237,0.0004784752,0.00007838353,0.0001833582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002606641,0.0001036183,0.001633511,0.0000604151,0.00002292875,0.00002863337,0.00008737326,0.0003355712,0.9896827,0.000005902676,0.005384703,0.002394024],"study_design_scores_gemma":[0.001988227,0.0001893844,0.004112279,0.00001786511,0.00008015777,0.0000125575,0.00001875054,0.0008223737,0.7815334,0.00003558053,0.2107797,0.0004096594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868364,0.008231935,0.001653284,0.0001672979,0.0005475131,0.0003381895,0.0000458944,0.00001482119,0.002164614],"genre_scores_gemma":[0.9950605,0.0004682952,0.0003471889,0.001665643,0.0007158248,0.0001335861,0.00005681116,0.00007123119,0.001480906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2081492,"threshold_uncertainty_score":0.9999521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004033199956214738,"score_gpt":0.2082472584607526,"score_spread":0.2042140585045379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}