{"id":"W2161909900","doi":"10.2174/138955708784223512","title":"Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease","year":2008,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Institut National de la Santé et de la Recherche Médicale","keywords":"Disease; Alzheimer's disease; Amyloid (mycology); Amyloid β; Polyphenol; Amyloid beta; Toxicity; Medicine; Pharmacology; Chemistry; Biochemistry; Internal medicine; Pathology; Antioxidant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002041669,0.0006719163,0.0009176129,0.001176335,0.0002262203,0.0005920251,0.0004826176,0.0006524486,0.002487593],"category_scores_gemma":[0.000172128,0.0001906926,0.0003227644,0.001069244,0.0002423211,0.00062858,0.0003137418,0.0008300185,0.001844254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002646576,"about_ca_system_score_gemma":0.0003320733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003771831,"about_ca_topic_score_gemma":0.0008222453,"domain_scores_codex":[0.9999257,0.00001278665,0.000007994877,0.00001320903,0.00002973099,0.00001063408],"domain_scores_gemma":[0.9999412,0.00001796844,0.0000127969,0.000002689015,0.00001695372,0.000008442214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000176157,0.0002245775,0.0002541188,0.01303293,0.0001069263,0.0005654562,0.00007432186,0.0004901907,0.03472147,0.003439863,0.01017171,0.9367422],"study_design_scores_gemma":[0.00008669307,0.000530188,0.002499813,0.001777127,0.000205632,0.003300661,0.00008723064,0.0002723872,0.01494508,0.002832308,0.9734254,0.0000374959],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001465426,0.9962923,0.0002747293,0.0001387907,0.0001550337,0.000009145694,0.00001905656,0.00001348921,0.001632063],"genre_scores_gemma":[0.005111991,0.9922693,0.0005131201,0.0001404874,0.0001384083,0.00001241731,0.00003931503,0.000002286385,0.001772696],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002487593,"threshold_uncertainty_score":0.008321822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04235191725474031,"score_gpt":0.3578021533500633,"score_spread":0.315450236095323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}