{"id":"W2161984364","doi":"10.1371/journal.ppat.1003357","title":"LAB/NTAL Facilitates Fungal/PAMP-induced IL-12 and IFN-γ Production by Repressing β-Catenin Activation in Dendritic Cells","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; National Cancer Institute; U.S. Department of Health and Human Services; National Institutes of Health; Versus Arthritis; Wellcome Trust","keywords":"Biology; Cytokine; Cell biology; Cytotoxic T cell; Ex vivo; Interleukin 12; Dendritic cell; Immunology; Immunoreceptor tyrosine-based activation motif; Immune system; T cell; In vitro; T-cell receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000100988,0.0003226425,0.0002407037,0.000172366,0.000115232,0.0003446374,0.0001572901,0.0001673667,0.001236098],"category_scores_gemma":[0.00008013842,0.000147592,0.0001962537,0.00009354248,0.0002139573,0.0001897227,0.0002284233,0.0005425776,0.0003846802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002391878,"about_ca_system_score_gemma":0.0001883514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002862044,"about_ca_topic_score_gemma":0.0005066673,"domain_scores_codex":[0.999862,0.00002053273,0.00001754359,0.00003113752,0.00003019584,0.00003870049],"domain_scores_gemma":[0.9998753,0.00001038809,0.00004517681,0.00001490408,0.000009158292,0.00004502365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009140812,0.00001556902,0.00007128946,0.0000140105,0.000001161783,0.00001698931,0.000004250315,0.00001510502,0.9995723,0.00002282665,0.000008627198,0.0001663944],"study_design_scores_gemma":[0.00002433469,0.0001714405,0.002631561,0.000004301013,0.000008288127,0.0001209962,0.00002254649,0.0005994262,0.9954242,0.00002691257,0.0009632824,0.000002775651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972188,0.0006064635,0.00109128,0.00005388186,0.00001980319,0.00001368793,0.0003100841,0.00006232786,0.0006236149],"genre_scores_gemma":[0.996536,0.000304378,0.0009131428,0.00003879373,0.00001013646,0.00002392712,0.0003808501,0.00002008293,0.001772673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001236098,"threshold_uncertainty_score":0.004135191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01745454675693217,"score_gpt":0.2052111476933606,"score_spread":0.1877566009364284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}