{"id":"W2162013503","doi":"10.1016/j.exphem.2006.11.012","title":"Polycythemia vera is not initiated by JAK2 mutation","year":2006,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":199,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health; U.S. Department of Defense","keywords":"Polycythemia vera; Allele; Mutation; Somatic cell; Biology; Mutant; Erythropoietin; Haematopoiesis; Genetics; Mutation frequency; Germline mutation; Immunology; Stem cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002336205,0.0002423527,0.0003077583,0.0004254678,0.0002691892,0.0003973741,0.000226752,0.0006947493,0.002986453],"category_scores_gemma":[0.001107421,0.00015336,0.000151198,0.0002267837,0.0006790393,0.0002929271,0.0001892603,0.0007296104,0.0004581888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002129718,"about_ca_system_score_gemma":0.0001907777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002693338,"about_ca_topic_score_gemma":0.0001929635,"domain_scores_codex":[0.9996148,0.0001553564,0.00003217213,0.00006606891,0.00006258257,0.00006894069],"domain_scores_gemma":[0.9991398,0.0004685567,0.0001078987,0.0001487812,0.00003086845,0.0001041352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006103411,0.0009946612,0.04262651,0.000424808,0.0001297105,0.07506926,0.0002812599,0.0003240571,0.8289161,0.0092905,0.002709292,0.03313042],"study_design_scores_gemma":[0.001828485,0.004485776,0.178447,0.00008734555,0.0002252582,0.3271905,0.0002745944,0.003316481,0.4437151,0.004923033,0.03544267,0.00006370081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9805899,0.003443518,0.001538959,0.0004688306,0.000177478,0.0000623271,0.0004207013,0.0001245783,0.01317371],"genre_scores_gemma":[0.9985166,0.0003655577,0.0001877597,0.00005277969,0.0000507065,0.00001059009,0.0001604955,0.000006888567,0.000648653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002986453,"threshold_uncertainty_score":0.009990692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01997845871133661,"score_gpt":0.3134519333722287,"score_spread":0.2934734746608921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}