{"id":"W2162103674","doi":"10.1152/ajpheart.01206.2005","title":"Activation of cardiac AMP-activated protein kinase by LKB1 expression or chemical hypoxia is blunted by increased Akt activity","year":2006,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heritage Medical Research Clinic; University of Alberta","funders":"","keywords":"AMPK; Phosphorylation; Protein kinase A; Protein kinase B; AMP-activated protein kinase; Chemistry; Cell biology; Kinase; Biology; Internal medicine; Endocrinology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001538398,0.0002672182,0.0002963795,0.0001120982,0.0001538608,0.0003168058,0.0001914634,0.0001917766,0.002361839],"category_scores_gemma":[0.0001405769,0.0002303411,0.0002415384,0.0001017916,0.0003250055,0.0002816332,0.0002054609,0.0006246786,0.0005787853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000358952,"about_ca_system_score_gemma":0.0002952531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004603428,"about_ca_topic_score_gemma":0.0007646803,"domain_scores_codex":[0.9998649,0.00001461909,0.00001601354,0.00002097646,0.00003569196,0.00004785532],"domain_scores_gemma":[0.9998885,0.00001404396,0.00004194633,0.00001151549,0.000008756972,0.00003518602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005365299,0.00005190483,0.0002997718,0.00005477011,0.000006974031,0.00005637752,0.00001622195,0.00002984853,0.9977925,0.000187917,0.00007283453,0.0008943086],"study_design_scores_gemma":[0.0001086087,0.0008549669,0.01290845,0.00001890957,0.00002011675,0.0003921086,0.00005874686,0.0006994166,0.9812557,0.0001043861,0.003572163,0.000006380388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996243,0.001329197,0.0005176296,0.0001789078,0.00006700914,0.00001305735,0.000222375,0.00003602617,0.001392832],"genre_scores_gemma":[0.9933599,0.001278704,0.001040652,0.0001129341,0.00003456774,0.00004562928,0.0006654689,0.00001732859,0.003444743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002361839,"threshold_uncertainty_score":0.007901132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006447650741411774,"score_gpt":0.2307868830672078,"score_spread":0.2243392323257961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}